| Discovery of isoxazolyl-based inhibitors of Plasmodium falciparum cGMP-dependent protein kinase SU Mahmood, H Cheng, SR Tummalapalli, R Chakrasali, ... RSC Medicinal Chemistry 11 (1), 98-101, 2020 | 11 | 2020 |
| Expression, purification, and inhibition profile of dihydrofolate reductase from the filarial nematode Wuchereria bancrofti AM Tobias, D Toska, K Lange, T Eck, R Bhat, CA Janson, DP Rotella, ... PloS one 13 (5), e0197173, 2018 | 11 | 2018 |
| Characterization of Competitive Inhibitors of Plasmodium falciparum cGMP‐Dependent Protein Kinase** T Eck, M Laureano de Souza, M Delvillar, K Ashraf, ... ChemBioChem 23 (7), e202100704, 2022 | 4 | 2022 |
| Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase RRY Bheemanaboina, ML De Souza, ML Gonzalez, SU Mahmood, T Eck, ... ACS Medicinal Chemistry Letters 12 (12), 1962-1967, 2021 | 3 | 2021 |
| A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs T Kreiss, T Eck, B Hart, S Tummalapalli, D Rotella, J Siekierka PLoS Neglected Tropical Diseases 16 (3), e0010216, 2022 | 1 | 2022 |
| Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials JA Gilleran, K Ashraf, M Delvillar, T Eck, R Fondekar, EB Miller, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
| Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate K Lange, KM Frey, T Eck, CA Janson, U Gubler, NM Goodey PLOS Neglected Tropical Diseases 17 (4), e0011303, 2023 | | 2023 |
| The Effects of Chitinase-1 on Brugia malayi R Maloney, J Siekierka, T Eck | | 2023 |
| Discovery of imidazole-based inhibitors of P. falciparum cGMP-dependent protein kinase RR Yadav Bheemanaboina, ML de Souza, ML Gonzalez, SU Mahmood, ... bioRxiv, 2021.11. 05.467463, 2021 | | 2021 |
| Discovery of novel potent, cell-permeable inhibitors of P. falciparum cGMP-dependent protein kinase RR Yadav Bheemanaboina, ML Gonzalez, SU Mahmood, T Eck, T Kreiss, ... bioRxiv, 2021.08. 24.457553, 2021 | | 2021 |
| Characterization of novel competitive inhibitors of P. falciparum cGMP-dependent protein kinase T Eck, ML de Souza, RR Yadav Bheemanaboina, R Chakrasali, T Kreiss, ... bioRxiv, 2021.06. 24.449800, 2021 | | 2021 |
| Mutational analysis confirms the presence of distal inhibitor-selectivity determining residues in B. stearothermophilus dihydrofolate reductase T Eck, S Patel, T Candela, M Little, NE Reis, U Liyanagunawardana, ... Archives of biochemistry and biophysics 692, 108545, 2020 | | 2020 |
| The Effects of Active Site and Allosteric Residues on Catalysis and Inhibitor Selectivity in the Bacillus stearothennophilus Dihydrofolate Reductase T Eck | | 2019 |
| Effect of Non‐Active Site Amino Acid Residues on Inhibitor Selectivity T Eck, U Gubler, N Goodey The FASEB Journal 32, 791.10-791.10, 2018 | | 2018 |
