ATP13A2 deficiency disrupts lysosomal polyamine export S van Veen, S Martin, C Van den Haute, V Benoy, J Lyons, R Vanhoutte, ... Nature 578 (7795), 419-424, 2020 | 258 | 2020 |
The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus I Vandecaetsbeek, P Vangheluwe, L Raeymaekers, F Wuytack, ... Cold Spring Harbor perspectives in biology 3 (5), a004184, 2011 | 256 | 2011 |
Modulating sarco (endo) plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: cell biological implications P Vangheluwe, L Raeymaekers, L Dode, F Wuytack Cell calcium 38 (3-4), 291-302, 2005 | 254 | 2005 |
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10 F Wauters, T Cornelissen, D Imberechts, S Martin, B Koentjoro, C Sue, ... Autophagy 16 (2), 203-222, 2020 | 177 | 2020 |
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78) A Estrada-Cuzcano, S Martin, T Chamova, M Synofzik, D Timmann, ... Brain 140 (2), 287-305, 2017 | 175 | 2017 |
Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species P Vangheluwe, M Schuermans, E Zádor, E Waelkens, L Raeymaekers, ... Biochemical Journal 389 (1), 151-159, 2005 | 164 | 2005 |
Necroptosis in immuno-oncology and cancer immunotherapy J Sprooten, P De Wijngaert, I Vanmeerbeek, S Martin, P Vangheluwe, ... Cells 9 (8), 1823, 2020 | 130 | 2020 |
The lysosome as a master regulator of iron metabolism F Rizzollo, S More, P Vangheluwe, P Agostinis Trends in biochemical sciences 46 (12), 960-975, 2021 | 128 | 2021 |
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency AK Tharkeshwar, J Trekker, W Vermeire, J Pauwels, R Sannerud, ... Scientific reports 7 (1), 41408, 2017 | 121 | 2017 |
Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure PA Gorski, SP Jang, D Jeong, A Lee, P Lee, JG Oh, V Chepurko, DK Yang, ... Circulation research 124 (9), e63-e80, 2019 | 119 | 2019 |
Replacement of the Muscle-Specific Sarcoplasmic Reticulum Ca2+-ATPase Isoform SERCA2a by the Nonmuscle SERCA2b Homologue Causes Mild Concentric … M Ver Heyen, S Heymans, G Antoons, T Reed, M Periasamy, B Awede, ... Circulation research 89 (9), 838-846, 2001 | 114 | 2001 |
Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness A Van den Bergh, A Vanderper, P Vangheluwe, F Desjardins, ... Cardiovascular research 77 (2), 371-379, 2008 | 110 | 2008 |
Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump I Vandecaetsbeek, M Trekels, M De Maeyer, H Ceulemans, E Lescrinier, ... Proceedings of the National Academy of Sciences 106 (44), 18533-18538, 2009 | 108 | 2009 |
Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling X Loyer, AM Gómez, P Milliez, M Fernandez-Velasco, P Vangheluwe, ... Circulation 117 (25), 3187-3198, 2008 | 102 | 2008 |
A lipid switch unlocks Parkinson’s disease-associated ATP13A2 T Holemans, DM Sřrensen, S van Veen, S Martin, D Hermans, ... Proceedings of the National Academy of Sciences 112 (29), 9040-9045, 2015 | 97 | 2015 |
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders S van Veen, DM Sřrensen, T Holemans, HW Holen, MG Palmgren, ... Frontiers in molecular neuroscience 7, 48, 2014 | 97 | 2014 |
Regulation of endoplasmic reticulum Ca2+ oscillations in mammalian eggs T Wakai, N Zhang, P Vangheluwe, RA Fissore Journal of cell science 126 (24), 5714-5724, 2013 | 95 | 2013 |
Intracellular Ca2+- and Mn2+-Transport ATPases P Vangheluwe, MR Sepulveda, L Missiaen, L Raeymaekers, F Wuytack, ... Chemical reviews 109 (10), 4733-4759, 2009 | 95 | 2009 |
An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAFV600E inhibitor-resistant metastatic melanoma cells S Martin, AM Dudek-Peric, AD Garg, H Roose, S Demirsoy, S Van Eygen, ... Autophagy 13 (9), 1512-1527, 2017 | 84 | 2017 |
ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress S Vrijsen, L Besora-Casals, S van Veen, J Zielich, C Van den Haute, ... Proceedings of the National Academy of Sciences 117 (49), 31198-31207, 2020 | 79 | 2020 |