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Elizabeth A Sweeny
Elizabeth A Sweeny
Department of Biochemistry, Medical College of Wisconsin
Verified email at mcw.edu
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Cited by
Cited by
Year
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
4582018
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
SN Gates, AL Yokom, JB Lin, ME Jackrel, AN Rizo, NM Kendsersky, ...
Science 357 (6348), 273-279, 2017
2682017
Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients
ME DeSantis, EH Leung, EA Sweeny, ME Jackrel, M Cushman-Nick, ...
Cell 151 (4), 778-793, 2012
2002012
A synergistic small-molecule combination directly eradicates diverse prion strain structures
BE Roberts, ML Duennwald, H Wang, C Chung, NP Lopreiato, ...
Nature chemical biology 5 (12), 936-946, 2009
1172009
Glyceraldehyde-3-phosphate dehydrogenase is a chaperone that allocates labile heme in cells
EA Sweeny, AB Singh, R Chakravarti, O Martinez-Guzman, A Saini, ...
Journal of Biological Chemistry 293 (37), 14557-14568, 2018
1132018
The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation
EA Sweeny, ME Jackrel, MS Go, MA Sochor, BM Razzo, ME DeSantis, ...
Molecular cell 57 (5), 836-849, 2015
1072015
Mechanistic and structural insights into the prion-disaggregase activity of Hsp104
EA Sweeny, J Shorter
Journal of molecular biology 428 (9), 1870-1885, 2016
1032016
Formation of Nitrogenase NifDK Tetramers in the Mitochondria of Saccharomyces cerevisiae
S Burén, EM Young, EA Sweeny, G Lopez-Torrejón, M Veldhuizen, ...
ACS Synthetic Biology 6 (6), 1043-1055, 2017
862017
Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells
A Ghosh, G Garee, EA Sweeny, Y Nakamura, DJ Stuehr
Proceedings of the National Academy of Sciences 115 (6), E1117-E1126, 2018
592018
GAPDH delivers heme to soluble guanylyl cyclase
Y Dai, EA Sweeny, S Schlanger, A Ghosh, DJ Stuehr
Journal of Biological Chemistry 295 (24), 8145-8154, 2020
572020
Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation
ME DeSantis, EA Sweeny, D Snead, EH Leung, MS Go, K Gupta, ...
Journal of Biological Chemistry 289 (2), 848-867, 2014
552014
Prion proteostasis: Hsp104 meets its supporting cast
EA Sweeny, J Shorter
Prion 2 (4), 135-140, 2008
52*2008
Mining disaggregase sequence space to safely counter TDP-43, FUS, and α-synuclein proteotoxicity
A Tariq, JB Lin, ME Jackrel, CD Hesketh, PJ Carman, KL Mack, ...
Cell reports 28 (8), 2080-2095. e6, 2019
472019
Purification of hsp104, a protein disaggregase
EA Sweeny, ME DeSantis, J Shorter
Journal of visualized experiments: JoVE, 3190, 2011
302011
GAPDH is involved in the heme-maturation of myoglobin and hemoglobin
B Tupta, E Stuehr, MP Sumi, EA Sweeny, B Smith, DJ Stuehr, A Ghosh
FASEB journal: official publication of the Federation of American Societies …, 2022
262022
Hsp104 and potentiated variants can operate as distinct nonprocessive translocases
CL Durie, JB Lin, NW Scull, KL Mack, ME Jackrel, EA Sweeny, ...
Biophysical Journal 116 (10), 1856-1872, 2019
232019
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting
EA Sweeny, A Tariq, E Gurpinar, MS Go, MA Sochor, ZY Kan, L Mayne, ...
Journal of Biological Chemistry 295 (6), 1517-1538, 2020
222020
Avidity for polypeptide binding by nucleotide-bound Hsp104 structures
CL Weaver, EC Duran, KL Mack, JB Lin, ME Jackrel, EA Sweeny, ...
Biochemistry 56 (15), 2071-2075, 2017
172017
Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones
EA Sweeny, S Schlanger, DJ Stuehr
Redox biology 36, 101656, 2020
152020
Nitric oxide and heme-NO stimulate superoxide production by NADPH oxidase 5
EA Sweeny, AP Hunt, AE Batka, S Schlanger, N Lehnert, DJ Stuehr
Free Radical Biology and Medicine 172, 252-263, 2021
132021
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