john mekalanos
john mekalanos
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A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
VL Miller, JJ Mekalanos
Journal of bacteriology 170 (6), 2575-2583, 1988
Lysogenic conversion by a filamentous phage encoding cholera toxin
MK Waldor, JJ Mekalanos
Science 272 (5270), 1910-1914, 1996
DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
JF Heidelberg, JA Eisen, WC Nelson, RA Clayton, ML Gwinn, RJ Dodson, ...
Nature 406 (6795), 477-483, 2000
Epidemiology, Genetics, and Ecology of ToxigenicVibrio cholerae
SM Faruque, MJ Albert, JJ Mekalanos
Microbiology and molecular biology reviews 62 (4), 1301-1314, 1998
Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system
S Pukatzki, AT Ma, D Sturtevant, B Krastins, D Sarracino, WC Nelson, ...
Proceedings of the National Academy of Sciences 103 (5), 1528-1533, 2006
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin.
RK Taylor, VL Miller, DB Furlong, JJ Mekalanos
Proceedings of the National Academy of Sciences 84 (9), 2833-2837, 1987
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus
JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou, CA Gifford, ...
Science 312 (5779), 1526-1530, 2006
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.
SI Miller, AM Kukral, JJ Mekalanos
Proceedings of the National Academy of Sciences 86 (13), 5054-5058, 1989
Environmental signals controlling expression of virulence determinants in bacteria
JJ Mekalanos
Journal of bacteriology 174 (1), 1-7, 1992
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae
J Zhu, MB Miller, RE Vance, M Dziejman, BL Bassler, JJ Mekalanos
Proceedings of the National Academy of Sciences 99 (5), 3129-3134, 2002
The origin of the Haitian cholera outbreak strain
CS Chin, J Sorenson, JB Harris, WP Robins, RC Charles, ...
New England Journal of Medicine 364 (1), 33-42, 2011
Selection of bacterial virulence genes that are specifically induced in host tissues
MJ Mahan, JM Slauch, JJ Mekalanos
Science 259 (5095), 686-688, 1993
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans.
DA Herrington, RH Hall, G Losonsky, JJ Mekalanos, RK Taylor, ...
The Journal of experimental medicine 168 (4), 1487-1492, 1988
Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development
JJ Mekalanos, DJ Swartz, GDN Pearson, N Harford, F Groyne, M de Wilde
Nature 306 (5943), 551-557, 1983
Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin
S Pukatzki, AT Ma, AT Revel, D Sturtevant, JJ Mekalanos
Proceedings of the National Academy of Sciences 104 (39), 15508-15513, 2007
Coordinate regulation and sensory transduction in the control of bacterial virulence
JF Miller, JJ Mekalanos, S Falkow
Science 243 (4893), 916-922, 1989
Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein
VL Miller, RK Taylor, JJ Mekalanos
cell 48 (2), 271-279, 1987
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin
PG Leiman, M Basler, UA Ramagopal, JB Bonanno, JM Sauder, ...
Proceedings of the National Academy of Sciences 106 (11), 4154-4159, 2009
Type VI secretion requires a dynamic contractile phage tail-like structure
M Basler, M Pilhofer, GP Henderson, GJ Jensen, JJ Mekalanos
Nature 483 (7388), 182-186, 2012
Quorum sensing-dependent biofilms enhance colonization in Vibrio cholerae
J Zhu, JJ Mekalanos
Developmental cell 5 (4), 647-656, 2003
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