Ganesh Anand
Ganesh Anand
Associate Professor, Department of Chemistry, The Pennsylvania State University
Verified email at
Cited by
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ...
Nature methods 16 (7), 595-602, 2019
PKA: a portrait of protein kinase dynamics
SS Taylor, J Yang, J Wu, NM Haste, E Radzio-Andzelm, G Anand
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 259-269, 2004
Dynamics of signaling by PKA
SS Taylor, C Kim, D Vigil, NM Haste, J Yang, J Wu, GS Anand
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 25-37, 2005
Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S
Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ...
Journal of Biological Chemistry 284 (5), 3076-3085, 2009
cAMP activation of PKA defines an ancient signaling mechanism
R Das, V Esposito, M Abu-Abed, GS Anand, SS Taylor, G Melacini
Proceedings of the National Academy of Sciences 104 (1), 93-98, 2007
The inner membrane histidine kinase EnvZ senses osmolality via helix‐coil transitions in the cytoplasm
LC Wang, LK Morgan, P Godakumbura, LJ Kenney, GS Anand
The EMBO journal 31 (11), 2648-2659, 2012
Salmonella enterica response regulator SsrB relieves H-NS silencing by displacing H-NS bound in polymerization mode and directly activates transcription
D Walthers, Y Li, Y Liu, G Anand, J Yan, LJ Kenney
Journal of Biological chemistry 286 (3), 1895-1902, 2011
Evolution of allostery in the cyclic nucleotide binding module
N Kannan, J Wu, GS Anand, S Yooseph, AF Neuwald, JC Venter, ...
Genome biology 8, 1-13, 2007
Activation of methylesterase CheB: evidence of a dual role for the regulatory domain
GS Anand, PN Goudreau, AM Stock
Biochemistry 37 (40), 14038-14047, 1998
Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the RIα subunit of protein kinase A
GS Anand, CA Hughes, JM Jones, SS Taylor, EA Komives
Journal of molecular biology 323 (2), 377-386, 2002
SARS-CoV-2 S protein: ACE2 interaction reveals novel allosteric targets
PV Raghuvamsi, NK Tulsian, F Samsudin, X Qian, K Purushotorman, ...
Elife 10, e63646, 2021
Identification of the protein kinase A regulatory RIα-catalytic subunit interface by amide H/2H exchange and protein docking
GS Anand, D Law, JG Mandell, AN Snead, I Tsigelny, SS Taylor, LFT Eyck, ...
Proceedings of the National Academy of Sciences 100 (23), 13264-13269, 2003
Mapping intersubunit interactions of the regulatory subunit (RIα) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS)
Y Hamuro, GS Anand, JS Kim, C Juliano, DD Stranz, SS Taylor, ...
Journal of molecular biology 340 (5), 1185-1196, 2004
Structure and dynamics of PKA signaling proteins.
C Kim, D Vigil, G Anand, SS Taylor
European journal of cell biology 85 (7), 651-654, 2006
Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments
M Hotchko, GS Anand, EA Komives, LF Ten Eyck
Protein Science 15 (3), 583-601, 2006
Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB
CA Hughes, JG Mandell, GS Anand, AM Stock, EA Komives
Journal of molecular biology 307 (4), 967-976, 2001
Allosteric network of cAMP-dependent protein kinase revealed by mutation of Tyr204 in the P+ 1 loop
J Yang, SM Garrod, MS Deal, GS Anand, VL Woods Jr, S Taylor
Journal of molecular biology 346 (1), 191-201, 2005
Conformational changes in intact dengue virus reveal serotype-specific expansion
XX Lim, A Chandramohan, XYE Lim, N Bag, KK Sharma, M Wirawan, ...
Nature communications 8 (1), 14339, 2017
Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design
S Badireddy, G Yunfeng, M Ritchie, P Akamine, J Wu, CW Kim, SS Taylor, ...
Molecular & Cellular Proteomics 10 (3), 2011
Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells
S Higuchi, Q Lin, J Wang, TK Lim, SB Joshi, GS Anand, MCM Chung, ...
Journal of bioscience and bioengineering 115 (3), 320-325, 2013
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