David B Hill
David B Hill
Joint Department of Biomedical Engineering, The Marsico Lung Institute, UNC CH
Verified email at - Homepage
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A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ...
Science 337 (6097), 937-941, 2012
A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms
H Matsui, VE Wagner, DB Hill, UE Schwab, TD Rogers, B Button, ...
Proceedings of the National Academy of Sciences 103 (48), 18131-18136, 2006
A biophysical basis for mucus solids concentration as a candidate biomarker for airways disease
DB Hill, PA Vasquez, J Mellnik, SA McKinley, A Vose, F Mu, ...
PloS one 9 (2), e87681, 2014
Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice
LA Hancock, CE Hennessy, GM Solomon, E Dobrinskikh, A Estrella, ...
Nature communications 9 (1), 5363, 2018
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis
CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ...
Science translational medicine 11 (486), eaav3488, 2019
Fast vesicle transport in PC12 neurites: velocities and forces
DB Hill, MJ Plaza, K Bonin, G Holzwarth
European Biophysics Journal 33, 623-632, 2004
Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH
DB Hill, RF Long, WJ Kissner, E Atieh, IC Garbarine, MR Markovetz, ...
European Respiratory Journal 52 (6), 2018
Physiology and pathophysiology of human airway mucus
DB Hill, B Button, M Rubinstein, RC Boucher
Physiological Reviews 102 (4), 1757-1836, 2022
An improved inhaled mucolytic to treat airway muco-obstructive diseases
C Ehre, ZL Rushton, B Wang, LN Hothem, CB Morrison, NC Fontana, ...
American journal of respiratory and critical care medicine 199 (2), 171-180, 2019
Force generation and dynamics of individual cilia under external loading
DB Hill, V Swaminathan, A Estes, J Cribb, ET O'Brien, CW Davis, ...
Biophysical journal 98 (1), 57-66, 2010
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells
JC Seagrave, HH Albrecht, DB Hill, DF Rogers, G Solomon
Respiratory research 13, 1-10, 2012
Monitoring airway mucus flow and ciliary activity with optical coherence tomography
AL Oldenburg, RK Chhetri, DB Hill, B Button
Biomedical optics express 3 (9), 1978-1992, 2012
Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis
KA Ramsey, ACH Chen, G Radicioni, R Lourie, M Martin, A Broomfield, ...
American journal of respiratory and critical care medicine 201 (6), 661-670, 2020
Establishment of respiratory air–liquid interface cultures and their use in studying mucin production, secretion, and function
DB Hill, B Button
Mucins: Methods and Protocols, 245-258, 2012
Model comparison and assessment for single particle tracking in biological fluids
M Lysy, NS Pillai, DB Hill, MG Forest, JWR Mellnik, PA Vasquez, ...
Journal of the American Statistical Association 111 (516), 1413-1426, 2016
Disruption and eradication of P. aeruginosa biofilms using nitric oxide-releasing chitosan oligosaccharides
KP Reighard, DB Hill, GA Dixon, BV Worley, MH Schoenfisch
Biofouling 31 (9-10), 775-787, 2015
Probing biological nanotopology via diffusion of weakly constrained plasmonic nanorods with optical coherence tomography
RK Chhetri, RL Blackmon, WC Wu, DB Hill, B Button, ...
Proceedings of the National Academy of Sciences 111 (41), E4289-E4297, 2014
Pulmonary fluid flow challenges for experimental and mathematical modeling
R Levy, DB Hill, MG Forest, JB Grotberg
American Zoologist 54 (6), 985-1000, 2014
Endotracheal tube mucus as a source of airway mucus for rheological study
MR Markovetz, DB Subramani, WJ Kissner, CB Morrison, IC Garbarine, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (4 …, 2019
Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration
CB Morrison, KM Shaffer, KC Araba, MR Markovetz, JA Wykoff, ...
European Respiratory Journal 59 (2), 2022
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