Tardigrades use intrinsically disordered proteins to survive desiccation TC Boothby, H Tapia, AH Brozena, S Piszkiewicz, AE Smith, I Giovannini, ... Molecular cell 65 (6), 975-984. e5, 2017 | 401 | 2017 |
Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade TC Boothby, JR Tenlen, FW Smith, JR Wang, KA Patanella, ... Proceedings of the National Academy of Sciences 112 (52), 15976-15981, 2015 | 205 | 2015 |
Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages P Sarkies, ME Selkirk, JT Jones, V Blok, T Boothby, B Goldstein, B Hanelt, ... PLoS biology 13 (2), e1002061, 2015 | 153 | 2015 |
Removal of retained introns regulates translation in the rapidly developing gametophyte of Marsilea vestita TC Boothby, RS Zipper, CM van der Weele, SM Wolniak Developmental cell 24 (5), 517-529, 2013 | 135 | 2013 |
The compact body plan of tardigrades evolved by the loss of a large body region FW Smith, TC Boothby, I Giovannini, L Rebecchi, EL Jockusch, ... Current Biology 26 (2), 224-229, 2016 | 120 | 2016 |
The biology of tardigrade disordered proteins in extreme stress tolerance C Hesgrove, TC Boothby Cell Communication and Signaling 18, 1-15, 2020 | 92 | 2020 |
LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching TC Fadero, TM Gerbich, K Rana, A Suzuki, M DiSalvo, KN Schaefer, ... Journal of Cell Biology 217 (5), 1869-1882, 2018 | 92 | 2018 |
Intrinsically disordered proteins and desiccation tolerance: elucidating functional and mechanistic underpinnings of anhydrobiosis TC Boothby, GJ Pielak BioEssays 39 (11), 1700119, 2017 | 80 | 2017 |
Protecting activity of desiccated enzymes S Piszkiewicz, KH Gunn, O Warmuth, A Propst, A Mehta, KH Nguyen, ... Protein Science 28 (5), 941-951, 2019 | 70 | 2019 |
Mechanisms and evolution of resistance to environmental extremes in animals TC Boothby EvoDevo 10 (1), 30, 2019 | 43 | 2019 |
Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance K Nguyen, S Kc, T Gonzalez, H Tapia, TC Boothby Communications Biology 5 (1), 1046, 2022 | 40 | 2022 |
Production of reactive oxygen species and involvement of bioprotectants during anhydrobiosis in the tardigrade Paramacrobiotus spatialis I Giovannini, TC Boothby, M Cesari, B Goldstein, R Guidetti, L Rebecchi Scientific Reports 12 (1), 1938, 2022 | 38 | 2022 |
Masked mRNA is stored with aggregated nuclear speckles and its asymmetric redistribution requires a homolog of mago nashi TC Boothby, SM Wolniak BMC Cell Biology 12, 1-17, 2011 | 30 | 2011 |
Water content influences the vitrified properties of CAHS proteins TC Boothby Molecular cell 81 (3), 411-413, 2021 | 21 | 2021 |
Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state MH Packebush, S Sanchez-Martinez, S Biswas, S Kc, KH Nguyen, ... Scientific Reports 13 (1), 4542, 2023 | 18 | 2023 |
Membrane and lipid metabolism plays an important role in desiccation resistance in the yeast Saccharomyces cerevisiae Q Ren, R Brenner, TC Boothby, Z Zhang BMC microbiology 20, 1-13, 2020 | 17 | 2020 |
Tardigrade CAHS proteins act as molecular Swiss Army knives to mediate desiccation tolerance through multiple mechanisms CS Hesgrove, KH Nguyen, S Biswas, CA Childs, KC Shraddha, ... bioRxiv, 2021.08. 16.456555, 2021 | 15 | 2021 |
The tardigrade protein CAHS D interacts with, but does not retain, water in hydrated and desiccated systems S Sanchez-Martinez, JF Ramirez, EK Meese, CA Childs, TC Boothby Scientific Reports 13 (1), 10449, 2023 | 12 | 2023 |
Desiccation of Hypsibius exemplaris TC Boothby Cold Spring Harbor Protocols 2018 (11), pdb. prot102327, 2018 | 12 | 2018 |
Reply to Bemm et al. and Arakawa: Identifying foreign genes in independent Hypsibius dujardini genome assemblies TC Boothby, B Goldstein Proceedings of the National Academy of Sciences 113 (22), E3058-E3061, 2016 | 12 | 2016 |