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Thomas C. Boothby
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Tardigrades use intrinsically disordered proteins to survive desiccation
TC Boothby, H Tapia, AH Brozena, S Piszkiewicz, AE Smith, I Giovannini, ...
Molecular cell 65 (6), 975-984. e5, 2017
4012017
Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade
TC Boothby, JR Tenlen, FW Smith, JR Wang, KA Patanella, ...
Proceedings of the National Academy of Sciences 112 (52), 15976-15981, 2015
2052015
Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages
P Sarkies, ME Selkirk, JT Jones, V Blok, T Boothby, B Goldstein, B Hanelt, ...
PLoS biology 13 (2), e1002061, 2015
1532015
Removal of retained introns regulates translation in the rapidly developing gametophyte of Marsilea vestita
TC Boothby, RS Zipper, CM van der Weele, SM Wolniak
Developmental cell 24 (5), 517-529, 2013
1352013
The compact body plan of tardigrades evolved by the loss of a large body region
FW Smith, TC Boothby, I Giovannini, L Rebecchi, EL Jockusch, ...
Current Biology 26 (2), 224-229, 2016
1202016
The biology of tardigrade disordered proteins in extreme stress tolerance
C Hesgrove, TC Boothby
Cell Communication and Signaling 18, 1-15, 2020
922020
LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching
TC Fadero, TM Gerbich, K Rana, A Suzuki, M DiSalvo, KN Schaefer, ...
Journal of Cell Biology 217 (5), 1869-1882, 2018
922018
Intrinsically disordered proteins and desiccation tolerance: elucidating functional and mechanistic underpinnings of anhydrobiosis
TC Boothby, GJ Pielak
BioEssays 39 (11), 1700119, 2017
802017
Protecting activity of desiccated enzymes
S Piszkiewicz, KH Gunn, O Warmuth, A Propst, A Mehta, KH Nguyen, ...
Protein Science 28 (5), 941-951, 2019
702019
Mechanisms and evolution of resistance to environmental extremes in animals
TC Boothby
EvoDevo 10 (1), 30, 2019
432019
Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance
K Nguyen, S Kc, T Gonzalez, H Tapia, TC Boothby
Communications Biology 5 (1), 1046, 2022
402022
Production of reactive oxygen species and involvement of bioprotectants during anhydrobiosis in the tardigrade Paramacrobiotus spatialis
I Giovannini, TC Boothby, M Cesari, B Goldstein, R Guidetti, L Rebecchi
Scientific Reports 12 (1), 1938, 2022
382022
Masked mRNA is stored with aggregated nuclear speckles and its asymmetric redistribution requires a homolog of mago nashi
TC Boothby, SM Wolniak
BMC Cell Biology 12, 1-17, 2011
302011
Water content influences the vitrified properties of CAHS proteins
TC Boothby
Molecular cell 81 (3), 411-413, 2021
212021
Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state
MH Packebush, S Sanchez-Martinez, S Biswas, S Kc, KH Nguyen, ...
Scientific Reports 13 (1), 4542, 2023
182023
Membrane and lipid metabolism plays an important role in desiccation resistance in the yeast Saccharomyces cerevisiae
Q Ren, R Brenner, TC Boothby, Z Zhang
BMC microbiology 20, 1-13, 2020
172020
Tardigrade CAHS proteins act as molecular Swiss Army knives to mediate desiccation tolerance through multiple mechanisms
CS Hesgrove, KH Nguyen, S Biswas, CA Childs, KC Shraddha, ...
bioRxiv, 2021.08. 16.456555, 2021
152021
The tardigrade protein CAHS D interacts with, but does not retain, water in hydrated and desiccated systems
S Sanchez-Martinez, JF Ramirez, EK Meese, CA Childs, TC Boothby
Scientific Reports 13 (1), 10449, 2023
122023
Desiccation of Hypsibius exemplaris
TC Boothby
Cold Spring Harbor Protocols 2018 (11), pdb. prot102327, 2018
122018
Reply to Bemm et al. and Arakawa: Identifying foreign genes in independent Hypsibius dujardini genome assemblies
TC Boothby, B Goldstein
Proceedings of the National Academy of Sciences 113 (22), E3058-E3061, 2016
122016
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Articles 1–20