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Margaret Alexander
Margaret Alexander
Assistant Professor; University of Wisconsin - Madison Medical Microbiology and Immunology
Verified email at wisc.edu - Homepage
Title
Cited by
Cited by
Year
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
M Alexander, R Hu, MC Runtsch, DA Kagele, TL Mosbruger, ...
Nature communications 6 (1), 7321, 2015
7622015
Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells
QY Ang, M Alexander, JC Newman, Y Tian, J Cai, V Upadhyay, ...
Cell 181 (6), 1263-1275. e16, 2020
4132020
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation
R Hu, DA Kagele, TB Huffaker, MC Runtsch, M Alexander, J Liu, E Bake, ...
Immunity 41 (4), 605-619, 2014
1732014
Human gut bacterial metabolism drives Th17 activation and colitis
Margaret Alexander, Qi Yan Ang, Renuka R. Nayak, Annamarie E. Bustion ...
Cell Host & Microbe 30 (1), 17 - 30.e9, 2022
1412022
Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes
KN Lam, M Alexander, PJ Turnbaugh
Cell host & microbe 26 (1), 22-34, 2019
1142019
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ...
Cell Reports 37 (5), 2021
1082021
The pretreatment gut microbiome is associated with lack of response to methotrexate in new‐onset rheumatoid arthritis
A Artacho, S Isaac, R Nayak, A Flor‐Duro, M Alexander, I Koo, ...
Arthritis & rheumatology 73 (6), 931-942, 2021
1072021
Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation
RR Nayak, M Alexander, I Deshpande, K Stapleton-Gray, B Rimal, ...
Cell host & microbe 29 (3), 362-377. e11, 2021
1002021
Deconstructing mechanisms of diet-microbiome-immune interactions
M Alexander, PJ Turnbaugh
Immunity 53 (2), 264-276, 2020
1002020
Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli
M Alexander, AG Ramstead, KM Bauer, SH Lee, MC Runtsch, J Wallace, ...
The Journal of Immunology 199 (10), 3559-3570, 2017
902017
Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade
TB Huffaker, SH Lee, WW Tang, JA Wallace, M Alexander, MC Runtsch, ...
Journal of Biological Chemistry 292 (45), 18530-18541, 2017
762017
Defective apical extrusion signaling contributes to aggressive tumor hallmarks
Y Gu, J Shea, G Slattum, MA Firpo, M Alexander, SJ Mulvihill, ...
Elife 4, e04069, 2015
692015
miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response
JA Wallace, DA Kagele, AM Eiring, CN Kim, R Hu, MC Runtsch, ...
Blood, The Journal of the American Society of Hematology 129 (23), 3074-3086, 2017
662017
MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis
MC Runtsch, R Hu, M Alexander, J Wallace, D Kagele, C Petersen, ...
Oncotarget 6 (30), 28556, 2015
612015
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease
MC Runtsch, MC Nelson, SH Lee, W Voth, M Alexander, R Hu, J Wallace, ...
PLoS genetics 15 (2), e1007970, 2019
572019
Noncoding RNAs and chronic inflammation: Micro‐managing the fire within
M Alexander, RM O'Connell
BioEssays 37 (9), 1005-1015, 2015
312015
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators
X Dong, BGH Guthrie, M Alexander, C Noecker, L Ramirez, NR Glasser, ...
Nature Communications 13 (1), 7624, 2022
262022
Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta
C Noecker, J Sanchez, JE Bisanz, V Escalante, M Alexander, K Trepka, ...
PLoS biology 21 (5), e3002125, 2023
172023
Perturbation of the human gut microbiome by a non-antibiotic drug contributes to the resolution of autoimmune disease
RR Nayak, M Alexander, K Stapleton-Grey, C Ubeda, JU Scher, ...
Biorxiv, 600155, 2019
162019
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis
KM Bauer, MC Nelson, WW Tang, TR Chiaro, DG Brown, A Ghazaryan, ...
JCI insight 7 (19), 2022
92022
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