Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 668 | 2015 |
Tunable drug release from hydrolytically degradable layer-by-layer thin films KC Wood, JQ Boedicker, DM Lynn, PT Hammond Langmuir 21 (4), 1603-1609, 2005 | 372 | 2005 |
Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films KC Wood, HF Chuang, RD Batten, DM Lynn, PT Hammond Proceedings of the National Academy of Sciences 103 (27), 10207-10212, 2006 | 332 | 2006 |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance CA Martz, KA Ottina, KR Singleton, JS Jasper, SE Wardell, ... Science Signaling 7 (357), ra121-ra121, 2014 | 220 | 2014 |
A family of hierarchically self‐assembling linear‐dendritic hybrid polymers for highly efficient targeted gene delivery KC Wood, SR Little, R Langer, PT Hammond Angewandte Chemie International Edition 44 (41), 6704-6708, 2005 | 205 | 2005 |
Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia KH Lin, PS Winter, A Xie, C Roth, CA Martz, EM Stein, GR Anderson, ... Scientific reports 6, 2016 | 183 | 2016 |
Electroactive controlled release thin films KC Wood, NS Zacharia, DJ Schmidt, SN Wrightman, BJ Andaya, ... Proceedings of the National Academy of Sciences 105 (7), 2280-2285, 2008 | 156 | 2008 |
ERRα-regulated lactate metabolism contributes to resistance to targeted therapies in breast cancer S Park, CY Chang, R Safi, X Liu, R Baldi, JS Jasper, GR Anderson, T Liu, ... Cell reports 15 (2), 323-335, 2016 | 135 | 2016 |
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers S Misale, I Bozic, J Tong, A Peraza-Penton, A Lallo, F Baldi, KH Lin, ... Nature communications 6 (1), 8305, 2015 | 131 | 2015 |
Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors GR Anderson, SE Wardell, M Cakir, C Yip, Y Ahn, M Ali, AP Yllanes, ... Nature Communications 9 (1), 1677, 2018 | 122 | 2018 |
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity RS Soderquist, L Crawford, E Liu, M Lu, A Agarwal, GR Anderson, KH Lin, ... Nature communications 9 (1), 3513, 2018 | 110 | 2018 |
Degradation of chlorinated organics by membrane‐immobilized nanosized metals DE Meyer, K Wood, LG Bachas, D Bhattacharyya Environmental progress 23 (3), 232-242, 2004 | 108 | 2004 |
Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide KC Wood, SM Azarin, W Arap, R Pasqualini, R Langer, PT Hammond Bioconjugate chemistry 19 (2), 403-405, 2008 | 107 | 2008 |
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence KR Singleton, L Crawford, E Tsui, HE Manchester, O Maertens, X Liu, ... Cell reports 21 (10), 2796-2812, 2017 | 98 | 2017 |
A landscape of therapeutic cooperativity in KRAS mutant cancers reveals principles for controlling tumor evolution GR Anderson, PS Winter, KH Lin, DP Nussbaum, M Cakir, EM Stein, ... Cell reports 20 (4), 999-1015, 2017 | 95 | 2017 |
Systematic dissection of the metabolic-apoptotic interface in AML reveals heme biosynthesis to be a regulator of drug sensitivity KH Lin, A Xie, JC Rutter, Y Ahn, JM Lloyd-Cowden, AG Nichols, ... Cell metabolism 29 (5), 1217-1231. e7, 2019 | 90 | 2019 |
RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis PS Winter, KA Sarosiek, KH Lin, M Meggendorfer, S Schnittger, A Letai, ... Science Signaling 7 (357), ra122-ra122, 2014 | 88 | 2014 |
Low-dose vertical inhibition of the RAF-MEK-ERK cascade causes apoptotic death of KRAS mutant cancers I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ... Cell reports 31 (11), 2020 | 75 | 2020 |
Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection AM Price, J Dai, Q Bazot, L Patel, PA Nikitin, R Djavadian, PS Winter, ... Elife 6, e22509, 2017 | 73 | 2017 |
PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers Z Zhong, S Sepramaniam, XH Chew, K Wood, MA Lee, B Madan, ... Oncogene 38 (40), 6662-6677, 2019 | 63 | 2019 |