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James Doroghazi
James Doroghazi
Computational Life Science Portfolio, Bayer CropScience
Verified email at bayer.com
Title
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Cited by
Year
A roadmap for natural product discovery based on large-scale genomics and metabolomics
JR Doroghazi, JC Albright, AW Goering, KS Ju, RR Haines, KA Tchalukov, ...
Nature chemical biology 10 (11), 963-968, 2014
5172014
Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes
JR Doroghazi, WW Metcalf
BMC genomics 14, 1-13, 2013
2492013
Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity
SB Kutluay, J Doroghazi, ME Roemer, SJ Triezenberg
Virology 373 (2), 239-247, 2008
2342008
Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes
KS Ju, J Gao, JR Doroghazi, KKA Wang, CJ Thibodeaux, S Li, E Metzger, ...
Proceedings of the National Academy of Sciences 112 (39), 12175-12180, 2015
2072015
Diversity and abundance of phosphonate biosynthetic genes in nature
X Yu, JR Doroghazi, SC Janga, JK Zhang, B Circello, BM Griffin, ...
Proceedings of the National Academy of Sciences 110 (51), 20759-20764, 2013
1672013
Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis
DP Labeda, CA Dunlap, X Rong, Y Huang, JR Doroghazi, KS Ju, ...
Antonie Van Leeuwenhoek 110, 563-583, 2017
1292017
Widespread homologous recombination within and between Streptomyces species
JR Doroghazi, DH Buckley
The ISME journal 4 (9), 1136-1143, 2010
1282010
Metabologenomics: correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer
AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ...
ACS central science 2 (2), 99-108, 2016
1272016
A Latitudinal Diversity Gradient in Terrestrial Bacteria of the Genus Streptomyces
CP Andam, JR Doroghazi, AN Campbell, PJ Kelly, MJ Choudoir, ...
MBio 7 (2), 10.1128/mbio. 02200-15, 2016
1152016
Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria
Q Zhang, JR Doroghazi, X Zhao, MC Walker, WA van der Donk
Applied and environmental microbiology 81 (13), 4339-4350, 2015
902015
The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles
CL Cox, JR Doroghazi, DA Mitchell
BMC genomics 16, 1-16, 2015
822015
Taxonomic evaluation of Streptomyces albus and related species using multilocus sequence analysis and proposals to emend the description of Streptomyces albus and …
DP Labeda, JR Doroghazi, KS Ju, WW Metcalf
International journal of systematic and evolutionary microbiology 64 (Pt_3 …, 2014
822014
Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways
KS Ju, JR Doroghazi, WW Metcalf
Journal of Industrial Microbiology and Biotechnology 41 (2), 345-356, 2014
742014
Nucleophilic 1, 4-additions for natural product discovery
CL Cox, JI Tietz, K Sokolowski, JO Melby, JR Doroghazi, DA Mitchell
ACS chemical biology 9 (9), 2014-2022, 2014
692014
Plantazolicin Is an Ultranarrow-Spectrum Antibiotic That Targets the Bacillus anthracis Membrane
KJ Molohon, PMB Saint-Vincent, S Park, JR Doroghazi, T Maxson, ...
ACS infectious diseases 2 (3), 207-220, 2015
622015
Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster
J Gao, KS Ju, X Yu, JE Velásquez, S Mukherjee, J Lee, C Zhao, BS Evans, ...
Angewandte Chemie 126 (5), 1358-1361, 2014
562014
A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria
Y Chen, I Ntai, KS Ju, M Unger, L Zamdborg, SJ Robinson, JR Doroghazi, ...
Journal of proteome research 11 (1), 85-94, 2012
522012
Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways
JC Albright, AW Goering, JR Doroghazi, WW Metcalf, NL Kelleher
Journal of Industrial Microbiology and Biotechnology 41 (2), 451-459, 2014
482014
Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic …
JR Doroghazi, DH Buckley
BMC genomics 15, 1-14, 2014
452014
Latitude delineates patterns of biogeography in terrestrial Streptomyces
MJ Choudoir, JR Doroghazi, DH Buckley
Environmental Microbiology 18 (12), 4931-4945, 2016
422016
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