A roadmap for natural product discovery based on large-scale genomics and metabolomics JR Doroghazi, JC Albright, AW Goering, KS Ju, RR Haines, KA Tchalukov, ... Nature chemical biology 10 (11), 963-968, 2014 | 535 | 2014 |
Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes JR Doroghazi, WW Metcalf BMC genomics 14, 1-13, 2013 | 268 | 2013 |
Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity SB Kutluay, J Doroghazi, ME Roemer, SJ Triezenberg Virology 373 (2), 239-247, 2008 | 245 | 2008 |
Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes KS Ju, J Gao, JR Doroghazi, KKA Wang, CJ Thibodeaux, S Li, E Metzger, ... Proceedings of the National Academy of Sciences 112 (39), 12175-12180, 2015 | 217 | 2015 |
Diversity and abundance of phosphonate biosynthetic genes in nature X Yu, JR Doroghazi, SC Janga, JK Zhang, B Circello, BM Griffin, ... Proceedings of the National Academy of Sciences 110 (51), 20759-20764, 2013 | 180 | 2013 |
Metabologenomics: correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ... ACS central science 2 (2), 99-108, 2016 | 138 | 2016 |
Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis DP Labeda, CA Dunlap, X Rong, Y Huang, JR Doroghazi, KS Ju, ... Antonie Van Leeuwenhoek 110, 563-583, 2017 | 137 | 2017 |
Widespread homologous recombination within and between Streptomyces species JR Doroghazi, DH Buckley The ISME journal 4 (9), 1136-1143, 2010 | 132 | 2010 |
A Latitudinal Diversity Gradient in Terrestrial Bacteria of the Genus Streptomyces CP Andam, JR Doroghazi, AN Campbell, PJ Kelly, MJ Choudoir, ... MBio 7 (2), 10.1128/mbio. 02200-15, 2016 | 123 | 2016 |
Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria Q Zhang, JR Doroghazi, X Zhao, MC Walker, WA van der Donk Applied and environmental microbiology 81 (13), 4339-4350, 2015 | 94 | 2015 |
Taxonomic evaluation of Streptomyces albus and related species using multilocus sequence analysis and proposals to emend the description of Streptomyces albus and … DP Labeda, JR Doroghazi, KS Ju, WW Metcalf International journal of systematic and evolutionary microbiology 64 (Pt_3 …, 2014 | 88 | 2014 |
The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles CL Cox, JR Doroghazi, DA Mitchell BMC genomics 16, 1-16, 2015 | 86 | 2015 |
Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways KS Ju, JR Doroghazi, WW Metcalf Journal of Industrial Microbiology and Biotechnology 41 (2), 345-356, 2014 | 77 | 2014 |
Nucleophilic 1, 4-additions for natural product discovery CL Cox, JI Tietz, K Sokolowski, JO Melby, JR Doroghazi, DA Mitchell ACS chemical biology 9 (9), 2014-2022, 2014 | 72 | 2014 |
Plantazolicin Is an Ultranarrow-Spectrum Antibiotic That Targets the Bacillus anthracis Membrane KJ Molohon, PMB Saint-Vincent, S Park, JR Doroghazi, T Maxson, ... ACS infectious diseases 2 (3), 207-220, 2015 | 68 | 2015 |
Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster J Gao, KS Ju, X Yu, JE Velásquez, S Mukherjee, J Lee, C Zhao, BS Evans, ... Angewandte Chemie 126 (5), 1358-1361, 2014 | 58 | 2014 |
A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria Y Chen, I Ntai, KS Ju, M Unger, L Zamdborg, SJ Robinson, JR Doroghazi, ... Journal of proteome research 11 (1), 85-94, 2012 | 56 | 2012 |
Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways JC Albright, AW Goering, JR Doroghazi, WW Metcalf, NL Kelleher Journal of Industrial Microbiology and Biotechnology 41 (2), 451-459, 2014 | 48 | 2014 |
Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic … JR Doroghazi, DH Buckley BMC genomics 15, 1-14, 2014 | 47 | 2014 |
Latitude delineates patterns of biogeography in terrestrial Streptomyces MJ Choudoir, JR Doroghazi, DH Buckley Environmental Microbiology 18 (12), 4931-4945, 2016 | 45 | 2016 |