Simoné Searle Downing
Simoné Searle Downing
Nelson Mandela University
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Nitrogen starvation of cyanobacteria results in the production of β-N-methylamino-L-alanine
S Downing, SA Banack, JS Metcalf, PA Cox, TG Downing
Toxicon 58 (2), 187-194, 2011
Distinguishing the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) from other diamino acids
SA Banack, JS Metcalf, Z Spáčil, TG Downing, S Downing, A Long, ...
Toxicon 57 (5), 730-738, 2011
Distinguishing the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) from its structural isomer 2, 4-diaminobutyric acid (2, 4-DAB)
SA Banack, TG Downing, Z Spácil, EL Purdie, JS Metcalf, S Downing, ...
Toxicon 56 (6), 868-879, 2010
The fate of the cyanobacterial toxin β-N-methylamino-L-alanine in freshwater mussels
S Downing, V Contardo-Jara, S Pflugmacher, TG Downing
Ecotoxicology and Environmental Safety 101, 51-58, 2014
A potential physiological role for cyanotoxins in cyanobacteria of arid environments
TG Downing, RR Phelan, S Downing
Journal of Arid Environments 112, 147-151, 2015
Improved sensitivity using liquid chromatography mass spectrometry (LC-MS) for detection of propyl chloroformate derivatised β-N-methylamino-L-alanine (BMAA) in cyanobacteria
M Esterhuizen-Londt, S Downing, TG Downing
Water Sa 37 (2), 2011
The Effect of Exogenous β-N-Methylamino-l-alanine on the Growth of Synechocystis PCC6803
S Downing, M van de Venter, TG Downing
Microbial ecology 63, 149-156, 2012
Environmental modulation of microcystin and β-N-methylamino-l-alanine as a function of nitrogen availability
LL Scott, S Downing, RR Phelan, TG Downing
Toxicon 87, 1-5, 2014
The metabolism of the non-proteinogenic amino acid β-N-methylamino-L-alanine (BMAA) in the cyanobacterium Synechocystis PCC6803
S Downing, TG Downing
Toxicon 115, 41-48, 2016
Investigating β-N-Methylamino-l-alanine Misincorporation in Human Cell Cultures: A Comparative Study with Known Amino Acid Analogues
R van Onselen, S Downing, G Kemp, T Downing
Toxins 9 (12), 400, 2017
The evaluation of BMAA inhalation as a potential exposure route using a rat model
LL Scott, S Downing, TG Downing
Neurotoxicity Research 33, 6-14, 2018
Response of antioxidant and biotransformation systems of selected freshwater mussels (Dreissena polymorpha, Anadonta cygnea, Unio tumidus, and Corbicula javanicus) to the …
V Contardo-Jara, SKB Otterstein, S Downing, TG Downing, ...
Toxicological & Environmental Chemistry 96 (3), 451-465, 2014
β-N-methylamino-L-alanine (BMAA) metabolism in the aquatic macrophyte Ceratophyllum demersum
S Downing, M Esterhuizen-Londt, TG Downing
Ecotoxicology and Environmental Safety 120, 88-92, 2015
Human Scalp Hair as an Indicator of Exposure to the Environmental Toxin β-N-Methylamino-l-alanine
S Downing, LL Scott, N Zguna, TG Downing
Toxins 10 (1), 14, 2017
Potential for dietary exposure to β-N-methylamino-L-alanine and microcystin from a freshwater system
LL Scott, S Downing, T Downing
Toxicon 150, 261-266, 2018
Metabolism of the neurotoxic amino acid β-N-methylamino-L-alanine in human cell culture models
S Downing, R Van Onselen, G Kemp, TG Downing
Toxicon 168, 131-139, 2019
Confirmation of the role of β-N-methylamino-L-alanine (BMAA) in nitrogen metabolism of cyanobacteria
TG Downing, S Downing
The Occurrence and Environmental Fate of Cyanobacterial Β-N-methylamino-L-alanine and Consequential Potential Human Exposure: Report to the Water Research Commission
TG Downing, M Esterhuizen-Londt, S Downing
Water Research Commission, 2013
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