Non-coding RNAs in human disease M Esteller Nature reviews genetics 12 (12), 861-874, 2011 | 5366 | 2011 |
Epigenetics in cancer M Esteller New England Journal of Medicine 358 (11), 1148-1159, 2008 | 4831 | 2008 |
Epigenetic differences arise during the lifetime of monozygotic twins MF Fraga, E Ballestar, MF Paz, S Ropero, F Setien, ML Ballestar, ... Proceedings of the National Academy of Sciences 102 (30), 10604-10609, 2005 | 4517 | 2005 |
Epigenetic modifications and human disease A Portela, M Esteller Nature biotechnology 28 (10), 1057-1068, 2010 | 3528 | 2010 |
A gene hypermethylation profile of human cancer M Esteller, PG Corn, SB Baylin, JG Herman Cancer research 61 (8), 3225-3229, 2001 | 2890 | 2001 |
Inactivation of the DNA-Repair Gene MGMT and the Clinical Response of Gliomas to Alkylating Agents M Esteller, J Garcia-Foncillas, E Andion, SN Goodman, OF Hidalgo, ... New England Journal of Medicine 343 (19), 1350-1354, 2000 | 2847 | 2000 |
Cancer epigenomics: DNA methylomes and histone-modification maps M Esteller Nature reviews genetics 8 (4), 286-298, 2007 | 2840 | 2007 |
The Polycomb group protein EZH2 directly controls DNA methylation E Viré, C Brenner, R Deplus, L Blanchon, M Fraga, C Didelot, L Morey, ... Nature 439 (7078), 871-874, 2006 | 2625 | 2006 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2590 | 2010 |
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer MF Fraga, E Ballestar, A Villar-Garea, M Boix-Chornet, J Espada, ... Nature genetics 37 (4), 391-400, 2005 | 2431 | 2005 |
Gene-expression profiles in hereditary breast cancer I Hedenfalk, D Duggan, Y Chen, M Radmacher, M Bittner, R Simon, ... New England Journal of Medicine 344 (8), 539-548, 2001 | 2175 | 2001 |
Global epigenomic reconfiguration during mammalian brain development R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ... Science 341 (6146), 1237905, 2013 | 1983 | 2013 |
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1896 | 2016 |
DNA methylation and cancer M Kulis, M Esteller Advances in genetics 70, 27-56, 2010 | 1835 | 2010 |
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future M Esteller Oncogene 21 (35), 5427-5440, 2002 | 1704 | 2002 |
Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation is a Common Event in Primary Human Neoplasia M Esteller, SR Hamilton, PC Burger, SB Baylin, JG Herman Cancer research 59 (4), 793-797, 1999 | 1621 | 1999 |
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors M Esteller, JM Silva, G Dominguez, F Bonilla, X Matias-Guiu, E Lerma, ... JNCI: Journal of the National Cancer Institute 92 (7), 564-569, 2000 | 1546 | 2000 |
Cancer epigenetics reaches mainstream oncology M Rodríguez-Paredes, M Esteller Nature medicine 17 (3), 330-339, 2011 | 1511 | 2011 |
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors V Bolós, H Peinado, MA Pérez-Moreno, MF Fraga, M Esteller, A Cano Journal of cell science 116 (3), 499-511, 2003 | 1454 | 2003 |
A microRNA DNA methylation signature for human cancer metastasis A Lujambio, GA Calin, A Villanueva, S Ropero, M Sánchez-Céspedes, ... Proceedings of the National Academy of Sciences 105 (36), 13556-13561, 2008 | 1360 | 2008 |