Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation EM Barry, AA Weiss, IE Ehrmann, MC Gray, EL Hewlett, MS Goodwin Journal of bacteriology 173 (2), 720-726, 1991 | 218 | 1991 |
Adenylate cyclase toxin from Bordetella pertussis: identification and purification of the holotoxin molecule EL Hewlett, VM Gordon, JD McCaffery, WM Sutherland, MC Gray Journal of Biological Chemistry 264 (32), 19379-19384, 1989 | 194 | 1989 |
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis: different processes for interaction with and entry into target cells VM Gordon, WW Young Jr, SM Lechler, MC Gray, SH Leppla, EL Hewlett Journal of Biological Chemistry 264 (25), 14792-14796, 1989 | 139 | 1989 |
Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP! EL Hewlett, GM Donato, MC Gray Molecular microbiology 59 (2), 447-459, 2006 | 137 | 2006 |
Hemolytic activity of adenylate cyclase toxin fromBordetella pertussis IE Ehrmann, MC Gray, VM Gordon, LS Gray, EL Hewlett FEBS letters 278 (1), 79-83, 1991 | 131 | 1991 |
Hemolytic, but Not Cell-invasive Activity, of Adenylate Cyclase Toxin Is Selectively Affected by Differential Fatty-acylation in Escherichia coli (∗) M Hackett, CB Walker, L Guo, MC Gray, S Van Cuyk, A Ullmann, ... Journal of Biological Chemistry 270 (35), 20250-20253, 1995 | 129 | 1995 |
Distinct mechanisms for K+ efflux, intoxication, and hemolysis by Bordetella pertussis AC toxin M Gray, G Szabo, AS Otero, L Gray, E Hewlett Journal of Biological Chemistry 273 (29), 18260-18267, 1998 | 123 | 1998 |
Adenylate cyclase toxin from Bordetella pertussis. Conformational change associated with toxin activity. EL Hewlett, L Gray, M Allietta, I Ehrmann, VM Gordon, MC Gray Journal of Biological Chemistry 266 (26), 17503-17508, 1991 | 111 | 1991 |
Adenylate cyclase toxin from Bordetella pertussis produces ion conductance across artificial lipid bilayers in a calcium-and polarity-dependent manner. G Szabo, MC Gray, EL Hewlett Journal of biological chemistry 269 (36), 22496-22499, 1994 | 103 | 1994 |
Neutralizing Antibodies to Adenylate Cyclase Toxin Promote Phagocytosis of Bordetella pertussis by Human Neutrophils CL Weingart, PS Mobberley-Schuman, EL Hewlett, MC Gray, AA Weiss Infection and immunity 68 (12), 7152-7155, 2000 | 94 | 2000 |
Pertussis toxin effects on T lymphocytes are mediated through CD3 and not by pertussis toxin catalyzed modification of a G protein. LS Gray, KS Huber, MC Gray, EL Hewlett, VH Engelhard Journal of immunology (Baltimore, Md.: 1950) 142 (5), 1631-1638, 1989 | 93 | 1989 |
Mechanism of association of adenylate cyclase toxin with the surface of Bordetella pertussis: a role for toxin–filamentous haemagglutinin interaction FR Zaretzky, MC Gray, EL Hewlett Molecular microbiology 45 (6), 1589-1598, 2002 | 90 | 2002 |
Membrane Depolarization Prevents Cell Invasion by Bordetella pertussis Adenylate Cyclase Toxin (∗) AS Otero, BY Xiao, MC Gray, G Szabo, EL Hewlett Journal of Biological Chemistry 270 (17), 9695-9697, 1995 | 85 | 1995 |
Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin JC Eby, MC Gray, EL Hewlett Infection and immunity 82 (12), 5256-5269, 2014 | 83 | 2014 |
Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis MC Gray, GM Donato, FR Jones, T Kim, EL Hewlett Molecular microbiology 53 (6), 1709-1719, 2004 | 82 | 2004 |
Epitope Mapping of Monoclonal Antibodies againstBordetella pertussis Adenylate Cyclase Toxin SJ Lee, MC Gray, L Guo, P Sebo, EL Hewlett Infection and immunity 67 (5), 2090-2095, 1999 | 70 | 1999 |
Contribution of Bordetella filamentous hemagglutinin and adenylate cyclase toxin to suppression and evasion of interleukin-17-mediated inflammation MW Henderson, CS Inatsuka, AJ Sheets, CL Williams, DJ Benaron, ... Infection and immunity 80 (6), 2061-2075, 2012 | 69 | 2012 |
Quantification of the Adenylate Cyclase Toxin of Bordetella pertussis In Vitro and during Respiratory Infection JC Eby, MC Gray, JM Warfel, CD Paddock, TF Jones, SR Day, J Bowden, ... Infection and immunity 81 (5), 1390-1398, 2013 | 68 | 2013 |
Translocation-Specific Conformation of Adenylate Cyclase Toxin from Bordetella pertussis Inhibits Toxin-Mediated Hemolysis MC Gray, SJ Lee, LS Gray, FR Zaretzky, AS Otero, G Szabo, EL Hewlett Journal of bacteriology 183 (20), 5904-5910, 2001 | 52 | 2001 |
Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles GM Donato, CS Goldsmith, CD Paddock, JC Eby, MC Gray, EL Hewlett FEBS letters 586 (4), 459-465, 2012 | 51 | 2012 |