jonathan koff
jonathan koff
Associate Professor Yale University
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Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study
G Goshua, AB Pine, ML Meizlish, CH Chang, H Zhang, P Bahel, A Baluha, ...
The Lancet Haematology 7 (8), e575-e582, 2020
Phage therapy: a renewed approach to combat antibiotic-resistant bacteria
KE Kortright, BK Chan, JL Koff, PE Turner
Cell host & microbe 25 (2), 219-232, 2019
Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients
MJ Cox, M Allgaier, B Taylor, MS Baek, YJ Huang, RA Daly, U Karaoz, ...
PloS one 5 (6), e11044, 2010
A neutrophil activation signature predicts critical illness and mortality in COVID-19
ML Meizlish, AB Pine, JD Bishai, G Goshua, ER Nadelmann, M Simonov, ...
Blood advances 5 (5), 1164-1177, 2021
Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium
JL Koff, MXG Shao, IF Ueki, JA Nadel
American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (6 …, 2008
Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice
CK Wong, CA Smith, K Sakamoto, N Kaminski, JL Koff, DR Goldstein
The Journal of Immunology 199 (3), 1060-1068, 2017
Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis
Y Zhou, JY Lee, CM Lee, WK Cho, MJ Kang, JL Koff, PO Yoon, J Chae, ...
Journal of Biological Chemistry 287 (50), 41991-42000, 2012
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade
JL Koff, MXG Shao, S Kim, IF Ueki, JA Nadel
The Journal of Immunology 177 (12), 8693-8700, 2006
Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium
IF Ueki, G Min-Oo, A Kalinowski, E Ballon-Landa, LL Lanier, JA Nadel, ...
Journal of Experimental Medicine 210 (10), 1929-1936, 2013
TGF‐β: master regulator of inflammation and fibrosis
AG Stewart, B Thomas, J Koff
Respirology 23 (12), 1096-1097, 2018
Regulation of interleukin-8 via an airway epithelial signaling cascade
T Nakanaga, JA Nadel, IF Ueki, JL Koff, MXG Shao
American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (5 …, 2007
Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation
P Zhang, J Cheng, S Zou, AD D'Souza, JL Koff, J Lu, PJ Lee, DS Krause, ...
Nature communications 6 (1), 6221, 2015
A clinic blueprint for post-coronavirus disease 2019 RECOVERY: learning from the past, looking to the future
DD Lutchmansingh, MP Knauert, DE Antin-Ozerkis, G Chupp, L Cohn, ...
Chest 159 (3), 949-958, 2021
The impact of pretransplant mechanical ventilation on short-and long-term survival after lung transplantation
JP Singer, PD Blanc, C Hoopes, JA Golden, JL Koff, LE Leard, S Cheng, ...
American Journal of Transplantation 11 (10), 2197-2204, 2011
Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway …
A Kalinowski, BT Galen, IF Ueki, Y Sun, A Mulenos, A Osafo-Addo, ...
Mucosal immunology 11 (3), 958-967, 2018
Neutrophil-derived IL-6 limits alveolar barrier disruption in experimental ventilator-induced lung injury
PJ Wolters, C Wray, RE Sutherland, SS Kim, J Koff, Y Mao, JA Frank
The Journal of Immunology 182 (12), 8056-8062, 2009
EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production
A Kalinowski, I Ueki, G Min-Oo, E Ballon-Landa, D Knoff, B Galen, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 307 (2 …, 2014
Cystic fibrosis transmembrane regulator modulators: implications for the management of depression and anxiety in cystic fibrosis
JS Talwalkar, JL Koff, HB Lee, CJ Britto, AM Mulenos, AM Georgiopoulos
Psychosomatics 58 (4), 343-354, 2017
Case report: a case of wood-smoke–related pulmonary disease
JV Diaz, J Koff, MB Gotway, S Nishimura, JR Balmes
Environmental health perspectives 114 (5), 759-762, 2006
Bacteriophage therapy for infections in CF
BK Chan, G Stanley, M Modak, JL Koff, PE Turner
Pediatric Pulmonology 56, S4-S9, 2021
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