Mikael Simons
Mikael Simons
Technical University Munich
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Ceramide triggers budding of exosome vesicles into multivesicular endosomes
K Trajkovic, C Hsu, S Chiantia, L Rajendran, D Wenzel, F Wieland, ...
Science 319 (5867), 1244-1247, 2008
Exosomes–vesicular carriers for intercellular communication
M Simons, G Raposo
Current opinion in cell biology 21 (4), 575-581, 2009
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
L Cantuti-Castelvetri, R Ojha, LD Pedro, M Djannatian, J Franz, ...
Science 370 (6518), 856-860, 2020
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
M Simons, P Keller, B De Strooper, K Beyreuther, CG Dotti, K Simons
Proceedings of the National Academy of Sciences 95 (11), 6460-6464, 1998
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
K Fassbender, M Simons, C Bergmann, M Stroick, D Lütjohann, P Keller, ...
Proceedings of the National Academy of Sciences 98 (10), 5856-5861, 2001
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C
C Hsu, Y Morohashi, S Yoshimura, N Manrique-Hoyos, SY Jung, ...
Journal of Cell Biology 189 (2), 223-232, 2010
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
D Fitzner, M Schnaars, D Van Rossum, G Krishnamoorthy, P Dibaj, ...
Journal of cell science 124 (3), 447-458, 2011
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte–neuron communication
C Frühbeis, D Fröhlich, WP Kuo, J Amphornrat, S Thilemann, AS Saab, ...
PLoS biology 11 (7), e1001604, 2013
Oligodendrocytes: myelination and axonal support
M Simons, KA Nave
Cold Spring Harbor perspectives in biology 8 (1), a020479, 2016
Cell type–and brain region–resolved mouse brain proteome
K Sharma, S Schmitt, CG Bergner, S Tyanova, N Kannaiyan, ...
Nature neuroscience 18 (12), 1819-1831, 2015
Microglia states and nomenclature: A field at its crossroads
RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ...
Neuron 110 (21), 3458-3483, 2022
Phase separation of FUS is suppressed by its nuclear import receptor and arginine methylation
M Hofweber, S Hutten, B Bourgeois, E Spreitzer, A Niedner-Boblenz, ...
Cell 173 (3), 706-719. e13, 2018
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: a 26‐week randomized, placebo‐controlled, double‐blind trial
M Simons, F Schwärzler, D Lütjohann, K Von Bergmann, K Beyreuther, ...
Annals of neurology 52 (3), 346-350, 2002
Age-related myelin degradation burdens the clearance function of microglia during aging
S Safaiyan, N Kannaiyan, N Snaidero, S Brioschi, K Biber, S Yona, ...
Nature neuroscience 19 (8), 995-998, 2016
Myelin in the central nervous system: structure, function, and pathology
C Stadelmann, S Timmler, A Barrantes-Freer, M Simons
Physiological reviews 99 (3), 1381-1431, 2019
Myelin membrane wrapping of CNS axons by PI (3, 4, 5) P3-dependent polarized growth at the inner tongue
N Snaidero, W Möbius, T Czopka, LHP Hekking, C Mathisen, D Verkleij, ...
Cell 156 (1), 277-290, 2014
Defective cholesterol clearance limits remyelination in the aged central nervous system
L Cantuti-Castelvetri, D Fitzner, M Bosch-Queralt, MT Weil, M Su, P Sen, ...
Science 359 (6376), 684-688, 2018
Cholesterol and Alzheimer’s disease: is there a link?
M Simons, P Keller, J Dichgans, JB Schulz
Neurology 57 (6), 1089-1093, 2001
Central nervous system myelin: structure, synthesis and assembly
S Aggarwal, L Yurlova, M Simons
Trends in cell biology 21 (10), 585-593, 2011
Assembly of myelin by association of proteolipid protein with cholesterol-and galactosylceramide-rich membrane domains
M Simons, EM Krämer, C Thiele, W Stoffel, J Trotter
The Journal of cell biology 151 (1), 143-154, 2000
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