Diet rapidly and reproducibly alters the human gut microbiome LA David, CF Maurice, RN Carmody, DB Gootenberg, JE Button, ... Nature 505 (7484), 559-563, 2014 | 10642 | 2014 |
Bile acid metabolites control TH17 and Treg cell differentiation S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ... Nature 576 (7785), 143-148, 2019 | 949 | 2019 |
A biosynthetic pathway for a prominent class of microbiota-derived bile acids AS Devlin, MA Fischbach Nature chemical biology 11 (9), 685-690, 2015 | 395 | 2015 |
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites D Paik, L Yao, Y Zhang, S Bae, GD D’Agostino, M Zhang, E Kim, ... Nature 603 (7903), 907-912, 2022 | 342 | 2022 |
Modulation of a circulating uremic solute via rational genetic manipulation of the gut microbiota AS Devlin, A Marcobal, D Dodd, S Nayfach, N Plummer, T Meyer, ... Cell host & microbe 20 (6), 709-715, 2016 | 276 | 2016 |
A selective gut bacterial bile salt hydrolase alters host metabolism L Yao, SC Seaton, S Ndousse-Fetter, AA Adhikari, N DiBenedetto, ... Elife 7, e37182, 2018 | 238 | 2018 |
A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1 W Li, S Hang, Y Fang, S Bae, Y Zhang, M Zhang, G Wang, MD McCurry, ... Cell host & microbe 29 (9), 1366-1377. e9, 2021 | 168 | 2021 |
Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects SN Chaudhari, DA Harris, H Aliakbarian, JN Luo, MT Henke, ... Nature chemical biology 17 (1), 20-29, 2021 | 116 | 2021 |
A microbial metabolite remodels the gut-liver axis following bariatric surgery SN Chaudhari, JN Luo, DA Harris, H Aliakbarian, L Yao, D Paik, ... Cell host & microbe 29 (3), 408-424. e7, 2021 | 111 | 2021 |
Development of a covalent inhibitor of gut bacterial bile salt hydrolases AA Adhikari, TCM Seegar, SB Ficarro, MD McCurry, D Ramachandran, ... Nature chemical biology 16 (3), 318-326, 2020 | 99 | 2020 |
δ-Sultone Formation Through Rh-Catalyzed C− H Insertion SA Wolckenhauer, AS Devlin, J Du Bois Organic Letters 9 (21), 4363-4366, 2007 | 98 | 2007 |
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling KM Schneider, LS Candels, JR Hov, M Myllys, R Hassan, CV Schneider, ... Nature Metabolism 3 (9), 1228-1241, 2021 | 84 | 2021 |
Chains of evidence from correlations to causal molecules in microbiome-linked diseases SN Chaudhari, MD McCurry, AS Devlin Nature chemical biology 17 (10), 1046-1056, 2021 | 60 | 2021 |
A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria L Yao, GD D’Agostino, J Park, S Hang, AA Adhikari, Y Zhang, W Li, ... Nature microbiology 7 (9), 1404-1418, 2022 | 46 | 2022 |
Modular synthesis of the pentacyclic core of batrachotoxin and select batrachotoxin analogue designs AS Devlin, J Du Bois Chemical Science 4 (3), 1059-1063, 2013 | 40 | 2013 |
A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases AA Adhikari, D Ramachandran, SN Chaudhari, CE Powell, W Li, ... ACS chemical biology 16 (8), 1401-1412, 2021 | 34 | 2021 |
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury DK Li, SN Chaudhari, Y Lee, M Sojoodi, AA Adhikari, L Zukerberg, ... Science Advances 8 (34), eabo2794, 2022 | 30 | 2022 |
Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ... Nature 579 (7798), E7, 2020 | 28 | 2020 |
Inhibition of sodium ion channel function with truncated forms of batrachotoxin T Toma, MM Logan, F Menard, AS Devlin, J Du Bois ACS chemical neuroscience 7 (10), 1463-1468, 2016 | 23 | 2016 |
Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas MD McCurry, GD D’Agostino, JT Walsh, JE Bisanz, I Zalosnik, X Dong, ... Cell, 2024 | 15 | 2024 |