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Le Shu
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Year
Co-regulatory networks of human serum proteins link genetics to disease
V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ...
Science 361 (6404), 769-773, 2018
4322018
Targeting BCAA catabolism to treat obesity-associated insulin resistance
M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu, M Chen, RM Wynn, ...
Diabetes 68 (9), 1730-1746, 2019
2322019
Exposure to the BPA-substitute bisphenol S causes unique alterations of germline function
Y Chen, L Shu, Z Qiu, DY Lee, SJ Settle, S Que Hee, D Telesca, X Yang, ...
PLoS genetics 12 (7), e1006223, 2016
1072016
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems
L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, LD Orozco, ...
BMC genomics 17, 1-16, 2016
1002016
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States
L Shu, KHK Chan, G Zhang, T Huan, Z Kurt, Y Zhao, V Codoni, ...
PLoS genetics 13 (9), e1007040, 2017
832017
Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration
D Arneson, A Bhattacharya, L Shu, VP Mäkinen, X Yang
BMC genomics 17, 1-9, 2016
642016
Multi-omics integration reveals molecular networks and regulators of psoriasis
Y Zhao, D Jhamb, L Shu, D Arneson, DK Rajpal, X Yang
BMC systems biology 13, 1-14, 2019
432019
Prenatal bisphenol A exposure in mice induces multitissue multiomics disruptions linking to cardiometabolic disorders
L Shu, Q Meng, G Diamante, B Tsai, YW Chen, A Mikhail, H Luk, B Ritz, ...
Endocrinology 160 (2), 409-429, 2019
422019
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes
AS Axelsson, T Mahdi, HA Nenonen, T Singh, S Hänzelmann, A Wendt, ...
Nature communications 8 (1), 15652, 2017
402017
Translating GWAS findings to novel therapeutic targets for coronary artery disease
L Shu, M Blencowe, X Yang
Frontiers in cardiovascular medicine 5, 56, 2018
392018
Multidimensional integrative genomics approaches to dissecting cardiovascular disease
D Arneson, L Shu, B Tsai, R Barrere-Cain, C Sun, X Yang
Frontiers in cardiovascular medicine 4, 8, 2017
332017
Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice
G Zhang, HR Byun, Z Ying, M Blencowe, Y Zhao, J Hong, L Shu, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (1), 165569, 2020
272020
Long-term effect of dietary fibre intake on glycosylated haemoglobin A1c level and glycaemic control status among Chinese patients with type 2 diabetes mellitus
L Yang, L Shu, J Jiang, H Qiu, G Zhao, Y Zhou, Q Jiang, Q Sun, G Qin, ...
Public health nutrition 17 (8), 1858-1864, 2014
262014
Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell–Dependent Endothelial Cell Apoptosis
G Ruffenach, E O’Connor, M Vaillancourt, J Hong, N Cao, S Sarji, ...
Hypertension 76 (3), 985-996, 2020
212020
Integrative genomics analysis unravels tissue-specific pathways, networks, and key regulators of blood pressure regulation
Y Zhao, M Blencowe, X Shi, L Shu, C Levian, IS Ahn, SK Kim, T Huan, ...
Frontiers in cardiovascular medicine 6, 21, 2019
162019
BCAA catabolism drives adipogenesis via an intermediate metabolite and promotes subcutaneous adipose tissue expansion during obesity
J Shao, Y Liu, X Zhang, L Shu, J Yu, S Yang, C Gao, C Wang, N Cao, ...
bioRxiv, 2022.08. 18.504380, 2022
52022
Bioinformatics principles for deciphering cardiovascular diseases
L Shu, D Arneson, X Yang
Elsevier, 2018
52018
Mergeomics: integration of diverse genomics resources to identify pathogenic perturbations to biological systems
L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, S Ripatti, ...
BioRxiv, 036012, 2016
52016
Mergeomics: Integrative Network Analysis of Omics Data
L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, LD Orozco, ...
32017
Association of CDKAL1 genetic polymorphism with glycosylated hemoglobin A1clevel among non-diabetic Chinese adults
JY Jiang, H Qiu, GM Zhao, Y Zhou, M Mo, L Shu
J Diabetes Metab 2 (166), 2, 2011
32011
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