Age-related remodelling of oesophageal epithelia by mutated cancer drivers A Yokoyama, N Kakiuchi, T Yoshizato, Y Nannya, H Suzuki, Y Takeuchi, ... Nature 565 (7739), 312-317, 2019 | 569 | 2019 |
Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation T Yoshizato, Y Nannya, Y Atsuta, Y Shiozawa, Y Iijima-Yamashita, ... Blood, The Journal of the American Society of Hematology 129 (17), 2347-2358, 2017 | 323 | 2017 |
Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity Y Kagoya, A Yoshimi, K Kataoka, M Nakagawa, K Kumano, S Arai, ... The Journal of clinical investigation 124 (2), 528-542, 2014 | 243 | 2014 |
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells S Goyama, J Schibler, L Cunningham, Y Zhang, Y Rao, N Nishimoto, ... The Journal of clinical investigation 123 (9), 3876-3888, 2013 | 230 | 2013 |
Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity K Kataoka, T Sato, A Yoshimi, S Goyama, T Tsuruta, H Kobayashi, ... Journal of Experimental Medicine 208 (12), 2403-2416, 2011 | 205 | 2011 |
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis N Kakiuchi, K Yoshida, M Uchino, T Kihara, K Akaki, Y Inoue, K Kawada, ... Nature 577 (7789), 260-265, 2020 | 203 | 2020 |
Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling Y Watatani, Y Sato, H Miyoshi, K Sakamoto, K Nishida, Y Gion, Y Nagata, ... Leukemia 33 (12), 2867-2883, 2019 | 198 | 2019 |
Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins A Yoshimi, S Goyama, N Watanabe-Okochi, Y Yoshiki, Y Nannya, E Nitta, ... Blood, The Journal of the American Society of Hematology 117 (13), 3617-3628, 2011 | 180 | 2011 |
A role for RUNX1 in hematopoiesis and myeloid leukemia M Ichikawa, A Yoshimi, M Nakagawa, N Nishimoto, N Watanabe-Okochi, ... International journal of hematology 97, 726-734, 2013 | 153 | 2013 |
AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis M Nakagawa, M Ichikawa, K Kumano, S Goyama, M Kawazu, T Asai, ... Blood 108 (10), 3329-3334, 2006 | 124 | 2006 |
Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells S Arai, A Yoshimi, M Shimabe, M Ichikawa, M Nakagawa, Y Imai, ... Blood, The Journal of the American Society of Hematology 117 (23), 6304-6314, 2011 | 117 | 2011 |
AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis M Ichikawa, S Goyama, T Asai, M Kawazu, M Nakagawa, M Takeshita, ... The Journal of Immunology 180 (7), 4402-4408, 2008 | 116 | 2008 |
Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis R Saiki, Y Momozawa, Y Nannya, MM Nakagawa, Y Ochi, T Yoshizato, ... Nature medicine 27 (7), 1239-1249, 2021 | 103 | 2021 |
Recurrent CDC25C mutations drive malignant transformation in FPD/AML A Yoshimi, T Toya, M Kawazu, T Ueno, A Tsukamoto, H Iizuka, ... Nature communications 5 (1), 4770, 2014 | 103 | 2014 |
Molecular classification and diagnostics of upper urinary tract urothelial carcinoma Y Fujii, Y Sato, H Suzuki, N Kakiuchi, T Yoshizato, AT Lenis, S Maekawa, ... Cancer Cell 39 (6), 793-809. e8, 2021 | 94 | 2021 |
Germ line DDX41 mutations define a unique subtype of myeloid neoplasms H Makishima, R Saiki, Y Nannya, S Korotev, C Gurnari, J Takeda, ... Blood 141 (5), 534-549, 2023 | 93 | 2023 |
Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice A Kon, S Yamazaki, Y Nannya, K Kataoka, Y Ota, MM Nakagawa, ... Blood, The Journal of the American Society of Hematology 131 (6), 621-635, 2018 | 87 | 2018 |
In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem-cell transplantation without ex vivo graft manipulation Y Kanda, K Oshima, Y Asano-Mori, K Kandabashi, M Nakagawa, ... Transplantation 79 (10), 1351-1357, 2005 | 80 | 2005 |
Combined Cohesin–RUNX1 deficiency synergistically perturbs chromatin looping and causes myelodysplastic syndromes Y Ochi, A Kon, T Sakata, MM Nakagawa, N Nakazawa, M Kakuta, ... Cancer discovery 10 (6), 836-853, 2020 | 71 | 2020 |
The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region S Goyama, Y Yamaguchi, Y Imai, M Kawazu, M Nakagawa, T Asai, ... Blood 104 (12), 3558-3564, 2004 | 68 | 2004 |