Benjamin H. Kwok
Benjamin H. Kwok
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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity
L Meng, R Mohan, BHB Kwok, M Elofsson, N Sin, CM Crews
Proceedings of the National Academy of Sciences 96 (18), 10403-10408, 1999
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
LC Kapitein, EJG Peterman, BH Kwok, JH Kim, TM Kapoor, CF Schmidt
Nature 435 (7038), 114-118, 2005
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
BHB Kwok, B Koh, MKI Ndubuisi, M Elofsson, CM Crews
Chemistry & biology 8 (8), 759-766, 2001
Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology
N Sin, KB Kim, M Elofsson, L Meng, H Auth, BHB Kwok, CM Crews
Bioorganic & medicinal chemistry letters 9 (15), 2283-2288, 1999
Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm
YG Han, BH Kwok, MJ Kernan
Current Biology 13 (19), 1679-1686, 2003
Eponemycin exerts its antitumor effect through the inhibition of proteasome function
L Meng, BHB Kwok, N Sin, CM Crews
Cancer Research 59 (12), 2798-2801, 1999
Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z-Enamides. Some Preliminary Findings as to SAR
S Lin, ZQ Yang, BHB Kwok, M Koldobskiy, CM Crews, SJ Danishefsky
Journal of the American Chemical Society 126 (20), 6347-6355, 2004
Microtubule cross-linking triggers the directional motility of kinesin-5
LC Kapitein, BH Kwok, JS Weinger, CF Schmidt, TM Kapoor, ...
The Journal of cell biology 182 (3), 421-428, 2008
Allosteric inhibition of kinesin-5 modulates its processive directional motility
BH Kwok, LC Kapitein, JH Kim, EJG Peterman, CF Schmidt, TM Kapoor
Nature chemical biology 2 (9), 480-485, 2006
Probing cell-division phenotype space and Polo-like kinase function using small molecules
U Peters, J Cherian, JH Kim, BH Kwok, TM Kapoor
Nature chemical biology 2 (11), 618-626, 2006
The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex
S Solinet, K Mahmud, SF Stewman, K Ben El Kadhi, B Decelle, L Talje, ...
Journal of Cell Biology 202 (2), 251-260, 2013
The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5
BH Kwok, JG Yang, TM Kapoor
Current biology 14 (19), 1783-1788, 2004
Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation
L Coutinho de Oliveira, L Volpon, AK Rahardjo, MJ Osborne, ...
Proceedings of the National Academy of Sciences 116 (48), 24056-24065, 2019
KIF14 binds tightly to microtubules and adopts a rigor-like conformation
K Arora, L Talje, AB Asenjo, P Andersen, K Atchia, M Joshi, H Sosa, ...
Journal of Molecular Biology 426 (17), 2997-3015, 2014
Microtubule flux: drivers wanted
BH Kwok, TM Kapoor
Current opinion in cell biology 19 (1), 36-42, 2007
Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate
D Trofimova, M Paydar, A Zara, L Talje, BH Kwok, JS Allingham
Nature communications 9 (1), 2628, 2018
Adaptive resistance to an inhibitor of chromosomal instability in human cancer cells
B Orr, L Talje, Z Liu, BH Kwok, DA Compton
Cell reports 17 (7), 1755-1763, 2016
Kinesin Kif2C in regulation of DNA double strand break dynamics and repair
S Zhu, M Paydar, F Wang, Y Li, L Wang, B Barrette, T Bessho, BH Kwok, ...
Elife 9, e53402, 2020
Differential regulation of ZEB1 and EMT by MAPK-interacting protein kinases (MNK) and eIF4E in pancreatic cancer
K Kumar, CR Chow, K Ebine, AD Arslan, B Kwok, DJ Bentrem, FD Eckerdt, ...
Molecular cancer research 14 (2), 216-227, 2016
Simplified Synthetic TMC‐95A/B Analogues Retain the Potency of Proteasome Inhibitory Activity
ZQ Yang, BHB Kwok, S Lin, MA Koldobskiy, CM Crews, SJ Danishefsky
ChemBioChem 4 (6), 508-513, 2003
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