| Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104 SN Gates, AL Yokom, JB Lin, ME Jackrel, AN Rizo, NM Kendsersky, ... Science 357 (6348), 273-279, 2017 | 268 | 2017 |
| Amyloid assembly and disassembly E Chuang, AM Hori, CD Hesketh, J Shorter Journal of Cell Science 131 (8), jcs189928, 2018 | 208 | 2018 |
| Mechanistic insights into Hsp104 potentiation MP Torrente, E Chuang, MM Noll, ME Jackrel, MS Go, J Shorter Journal of Biological Chemistry 291 (10), 5101-5115, 2016 | 45 | 2016 |
| Structure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding events K Michalska, K Zhang, ZM March, C Hatzos-Skintges, G Pintilie, L Bigelow, ... Structure 27 (3), 449-463. e7, 2019 | 34 | 2019 |
| Therapeutic genetic variation revealed in diverse Hsp104 homologs ZM March, K Sweeney, H Kim, X Yan, LM Castellano, ME Jackrel, JB Lin, ... elife 9, e57457, 2020 | 26 | 2020 |
| The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate RD Jones, C Enam, R Ibarra, HR Borror, KE Mostoller, EK Fredrickson, ... Molecular Biology of the Cell 31 (3), 221-233, 2020 | 20 | 2020 |
| Tuning Hsp104 specificity to selectively detoxify α-synuclein KL Mack, H Kim, EM Barbieri, JB Lin, S Braganza, ME Jackrel, JE DeNizio, ... Molecular cell 83 (18), 3314-3332. e9, 2023 | 17 | 2023 |
| Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3 RR Cupo, AN Rizo, GA Braun, E Tse, E Chuang, K Gupta, DR Southworth, ... Cell reports 40 (13), 2022 | 12 | 2022 |
| Case-study investigation of equine maternity via PCR-RFLP: A biochemistry laboratory experiment JT Millard, E Chuang, JS Lucas, EE Nagy, GT Davis Journal of chemical education 90 (11), 1518-1521, 2013 | 11 | 2013 |
| Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons G Wang, RJ Guasp, S Salam, E Chuang, A Morera, AJ Smart, D Jimenez, ... Elife 13, RP95443, 2024 | 5 | 2024 |
| Modulating material properties of cargo protein to probe exopher biology E Chuang, M Barai, BS Schuster, M Driscoll Biophysical Journal 123 (3), 217a-218a, 2024 | 1 | 2024 |
| Design principles to tailor Hsp104 therapeutics JB Lin, PJ Carman, CW Gambogi, NM Kendsersky, E Chuang, SN Gates, ... bioRxiv, 2024 | | 2024 |
| Defining a small-molecule stimulator of the human Hsp70-disaggregase system with selectivity for DnaJB proteins E Chuang, RR Cupo, JR Bevan, ML Rice, S Mao, EL Gorenberg, KL Mack, ... bioRxiv, 2024.01. 11.575109, 2024 | | 2024 |
| Pharmacological Stimulation of the Human Hsp70 Protein Disaggregase System E Chuang University of Pennsylvania, 2020 | | 2020 |
| Exploring and enhancing the metazoan disaggregase system to combat protein aggregation. E Chuang, M Salim, J Shorter MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
| Comparison of Crystal and Cryoem Structures of Hsp104 and ClpB Disaggregases A Joachimiak, K Michalska, K Zhang, Z March, C Hatzos-Skintges, ... PROTEIN SCIENCE 27, 32-33, 2018 | | 2018 |
| Characterizing the mechanics of Hsp104 (A503V) potentiation E Chuang, M Torrente, M Noll, M Jackrel, J Shorter ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
| Amplification of human DNA for probing DEB‐induced damage via a quantitative polymerase chain reaction E Chuang, JT Millard The FASEB Journal 27, 975.3-975.3, 2013 | | 2013 |
| Small Molecule Modulators of the Metazoan Disaggregase System M Salim, E Chuang, J Shorter | | |
