Recon3D enables a three-dimensional view of gene variation in human metabolism E Brunk, S Sahoo, DC Zielinski, A Altunkaya, A Dräger, N Mih, F Gatto, ... Nature biotechnology 36 (3), 272-281, 2018 | 686 | 2018 |
iML1515, a knowledgebase that computes Escherichia coli traits JM Monk, CJ Lloyd, E Brunk, N Mih, A Sastry, Z King, R Takeuchi, ... Nature biotechnology 35 (10), 904-908, 2017 | 517 | 2017 |
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models D Heckmann, CJ Lloyd, N Mih, Y Ha, DC Zielinski, ZB Haiman, ... Nature communications 9 (1), 5252, 2018 | 193 | 2018 |
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance ES Kavvas, E Catoiu, N Mih, JT Yurkovich, Y Seif, N Dillon, D Heckmann, ... Nature communications 9 (1), 4306, 2018 | 183 | 2018 |
Unique attributes of cyanobacterial metabolism revealed by improved genome-scale metabolic modeling and essential gene analysis JT Broddrick, BE Rubin, DG Welkie, N Du, N Mih, S Diamond, JJ Lee, ... Proceedings of the National Academy of Sciences 113 (51), E8344-E8353, 2016 | 128 | 2016 |
Global transcriptional regulatory network for Escherichia coli robustly connects gene expression to transcription factor activities X Fang, A Sastry, N Mih, D Kim, J Tan, JT Yurkovich, CJ Lloyd, Y Gao, ... Proceedings of the National Academy of Sciences 114 (38), 10286-10291, 2017 | 111 | 2017 |
Cellular responses to reactive oxygen species are predicted from molecular mechanisms L Yang, N Mih, A Anand, JH Park, J Tan, JT Yurkovich, JM Monk, CJ Lloyd, ... Proceedings of the National Academy of Sciences 116 (28), 14368-14373, 2019 | 103 | 2019 |
Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655 Y Gao, JT Yurkovich, SW Seo, I Kabimoldayev, A Dräger, K Chen, ... Nucleic Acids Research 46 (20), 10682-10696, 2018 | 99 | 2018 |
Thermosensitivity of growth is determined by chaperone-mediated proteome reallocation K Chen, Y Gao, N Mih, EJ O’Brien, L Yang, BO Palsson Proceedings of the National Academy of Sciences 114 (43), 11548-11553, 2017 | 93 | 2017 |
Systems biology of the structural proteome E Brunk, N Mih, J Monk, Z Zhang, EJ O’Brien, SE Bliven, K Chen, ... BMC systems biology 10, 1-16, 2016 | 61 | 2016 |
A computational knowledge-base elucidates the response of Staphylococcus aureus to different media types Y Seif, JM Monk, N Mih, H Tsunemoto, S Poudel, C Zuniga, J Broddrick, ... PLoS computational biology 15 (1), e1006644, 2019 | 56 | 2019 |
Escherichia coli B2 strains prevalent in inflammatory bowel disease patients have distinct metabolic capabilities that enable colonization of intestinal mucosa X Fang, JM Monk, N Mih, B Du, AV Sastry, E Kavvas, Y Seif, L Smarr, ... BMC systems biology 12, 1-10, 2018 | 50 | 2018 |
The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures KS Choudhary, N Mih, J Monk, E Kavvas, JT Yurkovich, G Sakoulas, ... Frontiers in Microbiology 9, 1082, 2018 | 40 | 2018 |
ssbio: a Python framework for structural systems biology N Mih, E Brunk, K Chen, E Catoiu, A Sastry, E Kavvas, JM Monk, Z Zhang, ... Bioinformatics 34 (12), 2155-2157, 2018 | 37 | 2018 |
Probing the selectivity and protein⋅ protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers J Bruegger, B Haushalter, A Vagstad, G Shakya, N Mih, CA Townsend, ... Chemistry & biology 20 (9), 1135-1146, 2013 | 37 | 2013 |
Genome‐scale metabolic modeling reveals key features of a minimal gene set JC Lachance, D Matteau, J Brodeur, CJ Lloyd, N Mih, ZA King, TF Knight, ... Molecular systems biology 17 (7), e10099, 2021 | 18 | 2021 |
Mechanisms for benzene dissociation through the excited state of T4 lysozyme L99A mutant VA Feher, JM Schiffer, DJ Mermelstein, N Mih, LCT Pierce, ... Biophysical Journal 116 (2), 205-214, 2019 | 18 | 2019 |
A multi-scale computational platform to mechanistically assess the effect of genetic variation on drug responses in human erythrocyte metabolism N Mih, E Brunk, A Bordbar, BO Palsson PLoS computational biology 12 (7), e1005039, 2016 | 16 | 2016 |
Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types K Chen, A Anand, C Olson, TE Sandberg, Y Gao, N Mih, BO Palsson PLoS computational biology 17 (1), e1008596, 2021 | 15 | 2021 |
Expanding the uses of genome‐scale models with protein structures N Mih, BO Palsson Molecular systems biology 15 (11), e8601, 2019 | 12 | 2019 |