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Gary B. Evans
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Quorum sensing controls adaptive immunity through the regulation of multiple CRISPR-Cas systems
AG Patterson, SA Jackson, C Taylor, GB Evans, GPC Salmond, ...
Molecular cell 64 (6), 1102-1108, 2016
2092016
Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli
V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ...
Journal of Biological Chemistry 280 (18), 18265-18273, 2005
1842005
Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase
A Lewandowicz, PC Tyler, GB Evans, RH Furneaux, VL Schramm
Journal of Biological Chemistry 278 (34), 31465-31468, 2003
1772003
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function
W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ...
Journal of Biological Chemistry 279 (18), 18103-18106, 2004
1762004
Potentiation of methicillin activity against methicillin-resistant Staphylococcus aureus by diterpenes
K Nicolson, G Evans, PW O'Toole
FEMS microbiology letters 179 (2), 233-239, 1999
1721999
Purine-less Death in Plasmodium falciparumInduced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase
GA Kicska, PC Tyler, GB Evans, RH Furneaux, VL Schramm, K Kim
Journal of Biological Chemistry 277 (5), 3226-3231, 2002
1632002
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins
LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ...
Journal of Biological Chemistry 280 (10), 9547-9554, 2005
1492005
Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum
GA Kicska, PC Tyler, GB Evans, RH Furneaux, K Kim, VL Schramm
Journal of Biological Chemistry 277 (5), 3219-3225, 2002
1312002
Exploring structure− activity relationships of transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (15), 3412-3423, 2003
1242003
Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine:  Convergent Synthesis of the Aza-C-nucleoside Immucillins
GB Evans, RH Furneaux, TL Hutchison, HS Kezar, PE Morris, ...
The Journal of organic chemistry 66 (17), 5723-5730, 2001
1232001
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (24), 5271-5276, 2003
1222003
Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases
GB Evans, RH Furneaux, GJ Gainsford, VL Schramm, PC Tyler
Tetrahedron 56 (19), 3053-3062, 2000
1082000
Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction
GB Evans, RH Furneaux, PC Tyler, VL Schramm
Organic letters 5 (20), 3639-3640, 2003
1032003
Azetidine Based Transition State Analogue Inhibitors of N-Ribosyl Hydrolases and Phosphorylases
GB Evans, RH Furneaux, B Greatrex, AS Murkin, VL Schramm, PC Tyler
Journal of medicinal chemistry 51 (4), 948-956, 2008
1002008
Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases
RW Miles, PC Tyler, GB Evans, RH Furneaux, DW Parkin, VL Schramm
Biochemistry 38 (40), 13147-13154, 1999
1001999
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5′-methylthioadenosine phosphorylase
I Basu, J Locker, MB Cassera, TJ Belbin, EF Merino, X Dong, I Hemeon, ...
Journal of biological chemistry 286 (6), 4902-4911, 2011
982011
Structural Rationale for the Affinity of Pico-and Femtomolar Transition State Analogues of Escherichia coli 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase*♦
JE Lee, V Singh, GB Evans, PC Tyler, RH Furneaux, KA Cornell, ...
Journal of Biological Chemistry 280 (18), 18274-18282, 2005
932005
Four generations of transition-state analogues for human purine nucleoside phosphorylase
MC Ho, W Shi, A Rinaldo-Matthis, PC Tyler, GB Evans, K Clinch, SC Almo, ...
Proceedings of the National Academy of Sciences 107 (11), 4805-4812, 2010
922010
Picomolar transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase and X-ray structure with MT-Immucillin-A
V Singh, W Shi, GB Evans, PC Tyler, RH Furneaux, SC Almo, ...
Biochemistry 43 (1), 9-18, 2004
902004
Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae
V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ...
Biochemistry 45 (43), 12929-12941, 2006
892006
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