Robert K. Bradley
Robert K. Bradley
Full Professor, Fred Hutchinson Cancer Center
Verified email at - Homepage
Cited by
Cited by
Integrative Clinical Genomics of Advanced Prostate Cancer
D Robinson, EM Van Allen, YM Wu, N Schultz, RJ Lonigro, JM Mosquera, ...
Cell 161 (5), 1215-1228, 2015
The molecular taxonomy of primary prostate cancer
A Abeshouse, J Ahn, R Akbani, A Ally, S Amin, CD Andry, M Annala, ...
Cell 163 (4), 1011-1025, 2015
Evolution of genes and genomes on the Drosophila phylogeny
AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ...
Nature 450 (7167), 203-218, 2007
< i> Braveheart</i>, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment
CA Klattenhoff, JC Scheuermann, LE Surface, RK Bradley, PA Fields, ...
Cell 152 (3), 570-583, 2013
RNA splicing factors as oncoproteins and tumour suppressors
H Dvinge, E Kim, O Abdel-Wahab, RK Bradley
Nature Reviews Cancer 16 (7), 413-430, 2016
SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition
E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ...
Cancer Cell 27 (5), 617-630, 2015
Fast statistical alignment
RK Bradley, A Roberts, M Smoot, S Juvekar, J Do, C Dewey, I Holmes, ...
PLoS computational biology 5 (5), e1000392, 2009
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ...
Nature medicine 22 (6), 672-678, 2016
Widespread intron retention diversifies most cancer transcriptomes
H Dvinge, RK Bradley
Genome Medicine 7 (1), 45, 2015
U2AF1 mutations alter splice site recognition in hematological malignancies
JO Ilagan, A Ramakrishnan, B Hayes, ME Murphy, AS Zebari, P Bradley, ...
Genome research 25 (1), 14-26, 2015
Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species
RK Bradley, XY Li, C Trapnell, S Davidson, L Pachter, HC Chu, LA Tonkin, ...
PLoS biology 8 (3), e1000343, 2010
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations
SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ...
Cancer Cell 34 (2), 225-241. e8, 2018
Spliceosomal disruption of the non-canonical BAF complex in cancer
D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ...
Nature 574 (7778), 432-436, 2019
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis
A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ...
Nature 574 (7777), 273-277, 2019
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ...
Cell 184 (15), 4032-4047. e31, 2021
Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A
CG Hubert, RK Bradley, Y Ding, CM Toledo, J Herman, K Skutt-Kakaria, ...
Genes & development 27 (9), 1032-1045, 2013
Massive Mitochondrial Gene Transfer in a Parasitic Flowering Plant Clade
Z Xi, Y Wang, RK Bradley, M Sugumaran, CJ Marx, JS Rest, CC Davis
PLOS Genetics 9 (2), e1003265, 2013
Horizontal transfer of expressed genes in a parasitic flowering plant
Z Xi, RK Bradley, KJ Wurdack, KM Wong, M Sugumaran, K Bomblies, ...
BMC genomics 13 (1), 227, 2012
Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution
RK Bradley, J Merkin, NJ Lambert, CB Burge
PLoS biology 10 (1), e1001229, 2012
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ...
Cancer cell 38 (2), 198-211. e8, 2020
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