leonardo sorci
leonardo sorci
Associate Professor, Polytechnic University of Marche, Italy
Verified email at - Homepage
Cited by
Cited by
Identification of a novel human nicotinamide mononucleotide adenylyltransferase
N Raffaelli, L Sorci, A Amici, M Emanuelli, F Mazzola, G Magni
Biochemical and biophysical research communications 297 (4), 835-840, 2002
NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration
L Conforti, G Fang, B Beirowski, MS Wang, L Sorci, S Asress, R Adalbert, ...
Cell Death & Differentiation 14 (1), 116-127, 2007
Diverse biological effects of the essential oil from Iranian Trachyspermum ammi
LA Vitali, D Beghelli, PCB Nya, O Bistoni, L Cappellacci, S Damiano, ...
Arabian Journal of Chemistry 9 (6), 775-786, 2016
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
E Mensà, M Guescini, A Giuliani, MG Bacalini, D Ramini, G Corleone, ...
Journal of extracellular vesicles 9 (1), 1725285, 2020
Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to …
L Sorci, F Cimadamore, S Scotti, R Petrelli, L Cappellacci, P Franchetti, ...
Biochemistry 46 (16), 4912-4922, 2007
Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon
DA Rodionov, X Li, IA Rodionova, C Yang, L Sorci, E Dervyn, ...
Nucleic acids research 36 (6), 2032-2046, 2008
Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis
L Sorci, D Martynowski, DA Rodionov, Y Eyobo, X Zogaj, KE Klose, ...
Proceedings of the National Academy of Sciences 106 (9), 3083-3088, 2009
Targeting NAD biosynthesis in bacterial pathogens: structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD
L Sorci, Y Pan, Y Eyobo, I Rodionova, N Huang, O Kurnasov, S Zhong, ...
Chemistry & biology 16 (8), 849-861, 2009
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues
S Ruggieri, G Orsomando, L Sorci, N Raffaelli
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (9), 1138-1149, 2015
NAD-biosynthetic and consuming enzymes as central players of metabolic regulation of innate and adaptive immune responses in cancer
V Audrito, A Managò, F Gaudino, L Sorci, VG Messana, N Raffaelli, ...
Frontiers in immunology 10, 1720, 2019
Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis
N Raffaelli, L Finaurini, F Mazzola, L Pucci, L Sorci, A Amici, G Magni
Biochemistry 43 (23), 7610-7617, 2004
Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria
IA Rodionova, BM Schuster, KM Guinn, L Sorci, DA Scott, X Li, I Kheterpal, ...
MBio 5 (1), 10.1128/mbio. 00747-13, 2014
Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family
L Galeazzi, P Bocci, A Amici, L Brunetti, S Ruggieri, M Romine, S Reed, ...
Journal of Biological Chemistry 286 (46), 40365-40375, 2011
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
A Managò, V Audrito, F Mazzola, L Sorci, F Gaudino, K Gizzi, N Vitale, ...
Nature Communications 10 (1), 4116, 2019
Glutamine versus ammonia utilization in the NAD synthetase family
J De Ingeniis, MD Kazanov, K Shatalin, MS Gelfand, AL Osterman, L Sorci
PloS one 7 (6), e39115, 2012
Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection
L Sorci, I Blaby, J De Ingeniis, S Gerdes, N Raffaelli, V de Crécy Lagard, ...
Journal of biological chemistry 285 (50), 39490-39499, 2010
Genomics and enzymology of NAD biosynthesis
L Sorci, O Kurnasov, DA Rodionov, AL Osterman
Comprehensive Natural Products II, 213-257, 2010
Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci
L Sorci, IK Blaby, IA Rodionova, J De Ingeniis, S Tkachenko, ...
Journal of bacteriology 195 (4), 726-732, 2013
Mexican sunflower (Tithonia diversifolia, Asteraceae) volatile oil as a selective inhibitor of Staphylococcus aureus nicotinate mononucleotide adenylyltransferase (NadD)
G Orsomando, S Agostinelli, M Bramucci, L Cappellacci, S Damiano, ...
Industrial Crops and Products 85, 181-189, 2016
Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement
N Huang, R Kolhatkar, Y Eyobo, L Sorci, I Rodionova, AL Osterman, ...
Journal of medicinal chemistry 53 (14), 5229-5239, 2010
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