Nicholas R Casewell
Nicholas R Casewell
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Complex cocktails: the evolutionary novelty of venoms
NR Casewell, W Wüster, FJ Vonk, RA Harrison, BG Fry
Trends in ecology & evolution, 2013
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
FJ Vonk, NR Casewell, CV Henkel, AM Heimberg, HJ Jansen, ...
Proceedings of the National Academy of Sciences 110 (51), 20651-20656, 2013
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes
TA Castoe, APJ De Koning, KT Hall, DC Card, DR Schield, MK Fujita, ...
Proceedings of the National Academy of Sciences 110 (51), 20645-20650, 2013
Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms
NR Casewell, SC Wagstaff, W Wüster, DAN Cook, FMS Bolton, SI King, ...
Proceedings of the National Academy of Sciences 111 (25), 9205-9210, 2014
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
DJ Williams, JM Gutiérrez, JJ Calvete, W Wüster, K Ratanabanangkoon, ...
Journal of proteomics 74 (9), 1735-1767, 2011
Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise
J Slagboom, J Kool, RA Harrison, NR Casewell
British journal of haematology 177 (6), 947-959, 2017
Domain loss facilitates accelerated evolution and neofunctionalization of duplicate snake venom metalloproteinase toxin genes
NR Casewell, SC Wagstaff, RA Harrison, C Renjifo, W Wüster
Molecular biology and evolution 28 (9), 2637-2649, 2011
Causes and consequences of snake venom variation
NR Casewell, TNW Jackson, AH Laustsen, K Sunagar
Trends in pharmacological sciences 41 (8), 570-581, 2020
A comparative genomics multitool for scientific discovery and conservation
Nature 587 (7833), 240-245, 2020
Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts
NR Casewell, RA Harrison, W Wüster, SC Wagstaff
BMC genomics 10 (1), 1-12, 2009
The structural and functional diversification of the Toxicofera reptile venom system
BG Fry, NR Casewell, W Wüster, N Vidal, B Young, TNW Jackson
Toxicon 60 (4), 434-448, 2012
Multifunctional toxins in snake venoms and therapeutic implications: From pain to hemorrhage and necrosis
CR Ferraz, A Arrahman, C Xie, NR Casewell, RJ Lewis, J Kool, ...
Frontiers in ecology and evolution 7, 218, 2019
Widespread convergence in toxin resistance by predictable molecular evolution
B Ujvari, NR Casewell, K Sunagar, K Arbuckle, W Wüster, N Lo, ...
Proceedings of the National Academy of Sciences 112 (38), 11911-11916, 2015
Dynamic evolution of venom proteins in squamate reptiles
NR Casewell, GA Huttley, W Wüster
Nature communications 3 (1), 1066, 2012
Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom
J Reyes-Velasco, DC Card, AL Andrew, KJ Shaney, RH Adams, ...
Molecular biology and evolution 32 (1), 173-183, 2015
Differential evolution and neofunctionalization of snake venom metalloprotease domains
A Brust, K Sunagar, EAB Undheim, I Vetter, DC Yang, NR Casewell, ...
Molecular & Cellular Proteomics 12 (3), 651-663, 2013
Pre-Clinical Assays Predict Pan-African Echis Viper Efficacy for a Species-Specific Antivenom
NR Casewell, DAN Cook, SC Wagstaff, A Nasidi, N Durfa, W Wüster, ...
PLoS neglected tropical diseases 4 (10), e851, 2010
Research strategies to improve snakebite treatment: Challenges and progress
RA Harrison, DA Cook, C Renjifo, NR Casewell, RB Currier, SC Wagstaff
Journal of proteomics 74 (9), 1768-1780, 2011
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa
RA Harrison, GO Oluoch, S Ainsworth, J Alsolaiss, F Bolton, AS Arias, ...
PLoS neglected tropical diseases 11 (10), e0005969, 2017
The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms
S Ainsworth, D Petras, M Engmark, RD Süssmuth, G Whiteley, ...
Journal of proteomics 172, 173-189, 2018
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