PPM1D mutations drive clonal hematopoiesis in response to cytotoxic chemotherapy JI Hsu, T Dayaram, A Tovy, E De Braekeleer, M Jeong, F Wang, J Zhang, ... Cell stem cell 23 (5), 700-713. e6, 2018 | 340 | 2018 |
A New Nuclear Function of the Entamoeba histolytica Glycolytic Enzyme Enolase: The Metabolic Regulation of Cytosine-5 Methyltransferase 2 (Dnmt2) Activity A Tovy, R Siman Tov, R Gaentzsch, M Helm, S Ankri PLoS pathogens 6 (2), e1000775, 2010 | 85 | 2010 |
p53 is essential for DNA methylation homeostasis in naive embryonic stem cells, and its loss promotes clonal heterogeneity A Tovy, A Spiro, R McCarthy, Z Shipony, Y Aylon, K Allton, E Ainbinder, ... Genes & development 31 (10), 959-972, 2017 | 68 | 2017 |
Glucose Starvation Boosts Entamoeba histolytica Virulence A Tovy, R Hertz, R Siman-Tov, S Syan, D Faust, N Guillen, S Ankri PLoS neglected tropical diseases 5 (8), e1247, 2011 | 51 | 2011 |
The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development T Gu, D Hao, J Woo, TW Huang, L Guo, X Lin, AG Guzman, A Tovy, ... Nature genetics 54 (5), 625-636, 2022 | 44 | 2022 |
Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor YH Huang, CW Chen, V Sundaramurthy, M Słabicki, D Hao, CJ Watson, ... Cancer discovery 12 (1), 220-235, 2022 | 44 | 2022 |
The Entamoeba histolytica Dnmt2 homolog (Ehmeth) confers resistance to nitrosative stress R Hertz, A Tovy, M Kirschenbaum, M Geffen, T Nozaki, N Adir, S Ankri Eukaryotic Cell 13 (4), 494-503, 2014 | 36 | 2014 |
Lats2 is critical for the pluripotency and proper differentiation of stem cells Y Aylon, A Sarver, A Tovy, E Ainbinder, M Oren Cell Death & Differentiation 21 (4), 624-633, 2014 | 30 | 2014 |
Tissue-biased expansion of DNMT3A-mutant clones in a mosaic individual is associated with conserved epigenetic erosion A Tovy, JM Reyes, MC Gundry, L Brunetti, H Lee-Six, M Petljak, HJ Park, ... Cell Stem Cell 27 (2), 326-335. e4, 2020 | 29 | 2020 |
In vitro tRNA Methylation Assay with the Entamoeba histolytica DNA and tRNA Methyltransferase Dnmt2 (Ehmeth) Enzyme A Tovy, B Hofmann, M Helm, S Ankri JoVE (Journal of Visualized Experiments), e2390, 2010 | 25 | 2010 |
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome A Tovy, C Rosas, AS Gaikwad, G Medrano, L Zhang, JM Reyes, ... Haematologica, 2021 | 21 | 2021 |
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis A Tovy, JM Reyes, L Zhang, YH Huang, C Rosas, AC Daquinag, ... Elife 11, e72359, 2022 | 19 | 2022 |
Structure analysis of Entamoeba histolytica enolase EC Schulz, M Tietzel, A Tovy, S Ankri, R Ficner Acta Crystallographica Section D: Biological Crystallography 67 (7), 619-627, 2011 | 15 | 2011 |
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation CW Chen, L Zhang, R Dutta, A Niroula, PG Miller, CJ Gibson, AG Bick, ... Cell Stem Cell 30 (11), 1503-1519. e8, 2023 | 14 | 2023 |
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ... Nature cell biology 25 (4), 528-539, 2023 | 14 | 2023 |
Epigenetics in The Unicellular Parasite Entamoeba Histolytica A Tovy, S Ankri Future microbiology 5 (12), 1875-1884, 2010 | 14 | 2010 |
The Entamoeba histolytica methylated LINE‐binding protein EhMLBP provides protection against heat shock S Katz, O Kushnir, A Tovy, R Siman Tov, S Ankri Cellular Microbiology 14 (1), 58-70, 2012 | 9 | 2012 |
Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation JM Reyes, A Tovy, L Zhang, AS Bortoletto, C Rosas, CW Chen, ... Iscience 27 (3), 2024 | 3 | 2024 |
Nearly a Third of Clonal Hematopoiesis-Associated DNMT3A Mutations Reduce Protein Stability and May be Associated with Poorer Prognosis YH Huang, A Tovy, V Sundaramurthy, J Su, J Hsu, L He, A Guzman, ... Blood 132, 1315, 2018 | 2 | 2018 |
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells L Zhang, JI Hsu, ED Braekeleer, CW Chen, TD Patel, AG Martell, ... eLife 12, RP91611, 2024 | | 2024 |