Rushika M. Perera
Rushika M. Perera
Associate Professor, UCSF
Verified email at - Homepage
Cited by
Cited by
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
J Son, CA Lyssiotis, H Ying, X Wang, S Hua, M Ligorio, RM Perera, ...
Nature 496 (7443), 101-105, 2013
Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
RM Perera, S Stoykova, BN Nicolay, KN Ross, J Fitamant, M Boukhali, ...
Nature 524 (7565), 361-365, 2015
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ...
Nature 581 (7806), 100-105, 2020
Autophagy in major human diseases
DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ...
The EMBO journal 40 (19), e108863, 2021
Structural basis of membrane invagination by F-BAR domains
A Frost, R Perera, A Roux, K Spasov, O Destaing, EH Egelman, ...
Cell 132 (5), 807-817, 2008
Stromal response to Hedgehog signaling restrains pancreatic cancer progression
JJ Lee, RM Perera, H Wang, DC Wu, XS Liu, S Han, J Fitamant, PD Jones, ...
Proceedings of the National Academy of Sciences 111 (30), E3091-E3100, 2014
The lysosome as a regulatory hub
RM Perera, R Zoncu
Annual review of cell and developmental biology 32, 223-253, 2016
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ...
Science 355 (6331), 1306-1311, 2017
A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes
R Zoncu, RM Perera, DM Balkin, M Pirruccello, D Toomre, P De Camilli
Cell 136 (6), 1110-1121, 2009
Beige adipocyte maintenance is regulated by autophagy-induced mitochondrial clearance
S Altshuler-Keylin, K Shinoda, Y Hasegawa, K Ikeda, H Hong, Q Kang, ...
Cell metabolism 24 (3), 402-419, 2016
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4, 5-bisphosphate
R Zoncu, RM Perera, R Sebastian, F Nakatsu, H Chen, T Balla, G Ayala, ...
Proceedings of the National Academy of Sciences 104 (10), 3793-3798, 2007
YAP inhibition restores hepatocyte differentiation in advanced HCC, leading to tumor regression
J Fitamant, F Kottakis, S Benhamouche, HS Tian, N Chuvin, ...
Cell reports 10 (10), 1692-1707, 2015
Pancreatic cancer metabolism: breaking it down to build it back up
RM Perera, N Bardeesy
Cancer discovery 5 (12), 1247-1261, 2015
Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages
RM Perera, R Zoncu, L Lucast, P De Camilli, D Toomre
Proceedings of the National Academy of Sciences 103 (51), 19332-19337, 2006
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
C Di Malta, D Siciliano, A Calcagni, J Monfregola, S Punzi, N Pastore, ...
Science 356 (6343), 1188-1192, 2017
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor–specific antibody generates enhanced …
RM Perera, Y Narita, FB Furnari, HK Gan, C Murone, M Ahlkvist, ...
Clinical Cancer Research 11 (17), 6390-6399, 2005
The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics
F Nakatsu, RM Perera, L Lucast, R Zoncu, J Domin, FB Gertler, D Toomre, ...
Journal of Cell Biology 190 (3), 307-315, 2010
Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478
TG Johns, RB Luwor, C Murone, F Walker, J Weinstock, AA Vitali, ...
Proceedings of the National Academy of Sciences 100 (26), 15871-15876, 2003
CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers
AM Heilmann, RM Perera, V Ecker, BN Nicolay, N Bardeesy, CH Benes, ...
Cancer research 74 (14), 3947-3958, 2014
Internalization, intracellular trafficking, biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody
RM Perera, R Zoncu, TG Johns, M Pypaert, FT Lee, I Mellman, LJ Old, ...
Neoplasia 9 (12), 1099-1110, 2007
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