A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso … P Cingolani, A Platts, LL Wang, M Coon, T Nguyen, L Wang, SJ Land, ... fly 6 (2), 80-92, 2012 | 9772 | 2012 |
Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift P Cingolani, VM Patel, M Coon, T Nguyen, SJ Land, DM Ruden, X Lu Frontiers in genetics 3, 35, 2012 | 957 | 2012 |
Ten putative contributors to the obesity epidemic EJ McAllister, NV Dhurandhar, SW Keith, LJ Aronne, J Barger, M Baskin, ... Critical reviews in food science and nutrition 49 (10), 868-913, 2009 | 928 | 2009 |
Putative contributors to the secular increase in obesity: exploring the roads less traveled SW Keith, DT Redden, PT Katzmarzyk, MM Boggiano, EC Hanlon, ... International journal of obesity 30 (11), 1585-1594, 2006 | 859 | 2006 |
Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution V Sollars, X Lu, L Xiao, X Wang, MD Garfinkel, DM Ruden Nature genetics 33 (1), 70-74, 2003 | 477 | 2003 |
Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene J Topol, DM Ruden, CS Parker Cell 42 (2), 527-537, 1985 | 312 | 1985 |
An examination of the association of selected toxic metals with total and central obesity indices: NHANES 99-02 MA Padilla, M Elobeid, DM Ruden, DB Allison International journal of environmental research and public health 7 (9 …, 2010 | 216 | 2010 |
Generating yeast transcriptional activators containing no yeast protein sequences DM Ruden, J Ma, Y Li, K Wood, M Ptashne Nature 350 (6315), 250-252, 1991 | 210 | 1991 |
Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis C Figueroa-Romero, J Hur, DE Bender, CE Delaney, MD Cataldo, ... PloS one 7 (12), e52672, 2012 | 185 | 2012 |
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress N Chia, L Wang, X Lu, MC Senut, CA Brenner, DM Ruden Epigenetics 6 (7), 853-856, 2011 | 175 | 2011 |
Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren A Sen, N Heredia, MC Senut, S Land, K Hollocher, X Lu, MO Dereski, ... Scientific reports 5 (1), 14466, 2015 | 173 | 2015 |
Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer DM Ruden, L Xiao, MD Garfinkel, X Lu Human molecular genetics 14 (suppl_1), R149-R155, 2005 | 166 | 2005 |
CloudAligner: a fast and full-featured MapReduce based tool for sequence mapping T Nguyen, W Shi, D Ruden BMC research notes 4, 1-7, 2011 | 162 | 2011 |
Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs X Lu, L Xiao, L Wang, DM Ruden Biochemical pharmacology 83 (8), 995-1004, 2012 | 152 | 2012 |
Radiation-induced epigenetic DNA methylation modification of radiation-response pathways DA Antwih, KM Gabbara, WD Lancaster, DM Ruden, SP Zielske Epigenetics 8 (8), 839-848, 2013 | 149 | 2013 |
Size‐dependent toxicity of gold nanoparticles on human embryonic stem cells and their neural derivatives MC Senut, Y Zhang, F Liu, A Sen, DM Ruden, G Mao Small 12 (5), 631-646, 2016 | 146 | 2016 |
PKD2 cation channel is required for directional sperm movement and male fertility Z Gao, DM Ruden, X Lu Current Biology 13 (24), 2175-2178, 2003 | 143 | 2003 |
Epigenetics of early-life lead exposure and effects on brain development MC Senut, P Cingolani, A Sen, A Kruger, A Shaik, H Hirsch, ST Suhr, ... Epigenomics 4 (6), 665-674, 2012 | 137 | 2012 |
Phthalate exposure and long-term epigenomic consequences: a review S Dutta, DK Haggerty, DA Rappolee, DM Ruden Frontiers in genetics 11, 499019, 2020 | 131 | 2020 |
Endocrine disruptors and obesity: an examination of selected persistent organic pollutants in the NHANES 1999–2002 data MA Elobeid, DW Brock, DB Allison, MA Padilla, DM Ruden International journal of environmental research and public health 7 (7 …, 2010 | 130 | 2010 |