Genome sequencing in microfabricated high-density picolitre reactors M Margulies, M Egholm, WE Altman, S Attiya, JS Bader, LA Bemben, ... Nature 437 (7057), 376-380, 2005 | 10726 | 2005 |
A core gut microbiome in obese and lean twins PJ Turnbaugh, M Hamady, T Yatsunenko, BL Cantarel, A Duncan, RE Ley, ... nature 457 (7228), 480-484, 2009 | 9443 | 2009 |
A draft sequence of the Neandertal genome RE Green, J Krause, AW Briggs, T Maricic, U Stenzel, M Kircher, ... science 328 (5979), 710-722, 2010 | 5153 | 2010 |
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide PE Nielsen, M Egholm, RH Berg, O Buchardt Science 254 (5037), 1497-1500, 1991 | 4720 | 1991 |
The tomato genome sequence provides insights into fleshy fruit evolution xx Tomato Genome Consortium Nature 485 (7400), 635, 2012 | 3356 | 2012 |
PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules M Egholm, O Buchardt, L Christensen, C Behrens, SM Freier, DA Driver, ... Nature 365 (6446), 566-568, 1993 | 2857 | 1993 |
The complete genome of an individual by massively parallel DNA sequencing DA Wheeler, M Srinivasan, M Egholm, Y Shen, L Chen, A McGuire, W He, ... nature 452 (7189), 872-876, 2008 | 2511 | 2008 |
The genome of the domesticated apple (Malus × domestica Borkh.) R Velasco, A Zharkikh, J Affourtit, A Dhingra, A Cestaro, A Kalyanaraman, ... Nature genetics 42 (10), 833-839, 2010 | 2402 | 2010 |
A metagenomic survey of microbes in honey bee colony collapse disorder DL Cox-Foster, S Conlan, EC Holmes, G Palacios, JD Evans, NA Moran, ... Science 318 (5848), 283-287, 2007 | 2271 | 2007 |
Comprehensive human genome amplification using multiple displacement amplification FB Dean, S Hosono, L Fang, X Wu, AF Faruqi, P Bray-Ward, Z Sun, ... Proceedings of the National Academy of Sciences 99 (8), 5261-5266, 2002 | 1887 | 2002 |
Paired-end mapping reveals extensive structural variation in the human genome JO Korbel, AE Urban, JP Affourtit, B Godwin, F Grubert, JF Simons, ... Science 318 (5849), 420-426, 2007 | 1552 | 2007 |
Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone M Egholm, O Buchardt, PE Nielsen, RH Berg Journal of the American Chemical Society 114 (5), 1895-1897, 1992 | 1352 | 1992 |
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes S Nejentsev, N Walker, D Riches, M Egholm, JA Todd Science 324 (5925), 387-389, 2009 | 1139 | 2009 |
Peptide nucleic acids PE Nielsen, O Buchardt, M Egholm, RH Berg US Patent 5,539,082, 1996 | 1118 | 1996 |
Analysis of one million base pairs of Neanderthal DNA RE Green, J Krause, SE Ptak, AW Briggs, MT Ronan, JF Simons, L Du, ... Nature 444 (7117), 330-336, 2006 | 1045 | 2006 |
Stability of peptide nucleic acids in human serum and cellular extracts VV Demidov, VN Potaman, MD Frank-Kamenetskil, M Egholm, O Buchard, ... Biochemical pharmacology 48 (6), 1310-1313, 1994 | 970 | 1994 |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility O Buchardt, M Egholm, PE Nielsen, RH Berg US Patent 5,714,331, 1998 | 853 | 1998 |
A new arenavirus in a cluster of fatal transplant-associated diseases G Palacios, J Druce, L Du, T Tran, C Birch, T Briese, S Conlan, PL Quan, ... New England journal of medicine 358 (10), 991-998, 2008 | 823 | 2008 |
Peptide nucleic acids having amino acid side chains O Buchardt, M Egholm, PE Nielsen, RH Berg US Patent 5,719,262, 1998 | 806 | 1998 |
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing RE Green, AS Malaspinas, J Krause, AW Briggs, PLF Johnson, C Uhler, ... Cell 134 (3), 416-426, 2008 | 788 | 2008 |