Andrew C. Hooker
Andrew C. Hooker
Professor of Pharmacometrics, Uppsala University
Verified email at - Homepage
Cited by
Cited by
Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models
M Bergstrand, AC Hooker, JE Wallin, MO Karlsson
The AAPS journal 13, 143-151, 2011
Modeling and simulation workbench for NONMEM: tutorial on Pirana, PsN, and Xpose
RJ Keizer, MO Karlsson, A Hooker
CPT: pharmacometrics & systems pharmacology 2 (6), 1-9, 2013
Quantitative magnetic resonance imaging analysis of neovasculature volume in carotid atherosclerotic plaque
W Kerwin, A Hooker, M Spilker, P Vicini, M Ferguson, T Hatsukami, ...
Circulation 107 (6), 851-856, 2003
Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method
AC Hooker, CE Staatz, MO Karlsson
Pharmaceutical research 24, 2187-2197, 2007
Model evaluation of continuous data pharmacometric models: metrics and graphics
THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ...
CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017
POPED, a software for optimal experiment design in population kinetics
M Foracchia, A Hooker, P Vicini, A Ruggeri
Computer methods and programs in biomedicine 74 (1), 29-46, 2004
PopED: an extended, parallelized, nonlinear mixed effects models optimal design tool
J Nyberg, S Ueckert, EA Strömberg, S Hennig, MO Karlsson, AC Hooker
Computer methods and programs in biomedicine 108 (2), 789-805, 2012
Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies
J Nyberg, C Bazzoli, K Ogungbenro, A Aliev, S Leonov, S Duffull, ...
British journal of clinical pharmacology 79 (1), 6-17, 2015
Improved utilization of ADAS-cog assessment data through item response theory based pharmacometric modeling
S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker, ...
Pharmaceutical research 31, 2152-2165, 2014
Population pharmacokinetic model for docetaxel in patients with varying degrees of liver function: incorporating cytochrome P450 3A activity measurements
AC Hooker, AJ Ten Tije, MA Carducci, J Weber, E Garrett‐Mayer, ...
Clinical Pharmacology & Therapeutics 84 (1), 111-118, 2008
Advanced methods for dose and regimen finding during drug development: summary of the EMA/EFPIA workshop on dose finding (London 4–5 December 2014)
FT Musuamba, E Manolis, N Holford, SYA Cheung, LE Friberg, ...
CPT: pharmacometrics & systems pharmacology 6 (7), 418-429, 2017
Robust population pharmacokinetic experiment design
MG Dodds, AC Hooker, P Vicini
Journal of Pharmacokinetics and Pharmacodynamics 32, 33-64, 2005
Simultaneous population optimal design for pharmacokinetic-pharmacodynamic experiments
A Hooker, P Vicini
The AAPS journal 7, E759-E785, 2005
A diagnostic tool for population models using non-compartmental analysis: the ncappc package for R
C Acharya, AC Hooker, GY Türkyılmaz, S Jönsson, MO Karlsson
Computer methods and programs in biomedicine 127, 83-93, 2016
An evaluation of population D-optimal designs via pharmacokinetic simulations
AC Hooker, M Foracchia, MG Dodds, P Vicini
Annals of biomedical engineering 31, 98-111, 2003
A fast method for testing covariates in population PK/PD models
A Khandelwal, K Harling, EN Jonsson, AC Hooker, MO Karlsson
The AAPS journal 13, 464-472, 2011
Simultaneous optimal experimental design on dose and sample times
J Nyberg, MO Karlsson, AC Hooker
Journal of pharmacokinetics and pharmacodynamics 36, 125-145, 2009
Modeling subpopulations with the $ MIXTURE subroutine in NONMEM: finding the individual probability of belonging to a subpopulation for the use in model analysis and improved …
KC Carlsson, RM Savi, AC Hooker, MO Karlsson
The AAPS journal 11, 148-154, 2009
A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066—estimating occupancy in the absence of a reference region
M Kågedal, Z Cselényi, S Nyberg, P Raboisson, L Ståhle, P Stenkrona, ...
Neuroimage 82, 160-169, 2013
Pharmacokinetics of P‐glycoprotein inhibition in the rat blood‐brain barrier
S Syvänen, A Hooker, O Rahman, H Wilking, G Blomquist, B Långström, ...
Journal of pharmaceutical sciences 97 (12), 5386-5400, 2008
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