Halogen atoms in the modern medicinal chemistry: hints for the drug design MZ Hernandes, SMT Cavalcanti, DRM Moreira, WF de Azevedo Junior, ... Current drug targets 11 (3), 303-314, 2010 | 678 | 2010 |
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi ACL Leite, RS de Lima, DRM Moreira, MVO Cardoso, ACG de Brito, ... Bioorganic & medicinal chemistry 14 (11), 3749-3757, 2006 | 144 | 2006 |
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ... European Journal of Medicinal Chemistry 86, 48-59, 2014 | 120 | 2014 |
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1, 2, 4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents JM dos Santos Filho, ACL Leite, BG de Oliveira, DRM Moreira, MS Lima, ... Bioorganic & medicinal chemistry 17 (18), 6682-6691, 2009 | 116 | 2009 |
Artemisinin–(Iso) quinoline Hybrids by C− H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria A Çapcı, MM Lorion, H Wang, N Simon, M Leidenberger, MC Borges Silva, ... Angewandte Chemie International Edition 58 (37), 13066-13079, 2019 | 92 | 2019 |
Approaches for the development of new anti-Trypanosoma cruzi agents DR Magalhaes Moreira, AC Lima Leite, RR Santos, MBP Soares Current Drug Targets 10 (3), 212-231, 2009 | 86 | 2009 |
Synthesis, Cruzain Docking, and in vitro Studies of Aryl‐4‐Oxothiazolylhydrazones Against Trypanosoma cruzi ACL Leite, DR de M. Moreira, MV de O. Cardoso, MZ Hernandes, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (9), 1339-1345, 2007 | 83 | 2007 |
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents A Inam, SM Siddiqui, TS Macedo, DRM Moreira, ACL Leite, MBP Soares, ... European Journal of Medicinal Chemistry 75, 67-76, 2014 | 78 | 2014 |
Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice DRM Moreira, SPM Costa, MZ Hernandes, MM Rabello, ... Journal of Medicinal Chemistry 55 (24), 10918-10936, 2012 | 75 | 2012 |
Antitumor and immunomodulatory activities of thiosemicarbazones and 1, 3-Thiazoles in Jurkat and HT-29 cells TAR Dos Santos, AC da Silva, EB Silva, PAT de Moraes Gomes, ... Biomedicine & Pharmacotherapy 82, 555-560, 2016 | 70 | 2016 |
Dimeric Flavonoids from Arrabidaea brachypoda and Assessment of Their Anti-Trypanosoma cruzi Activity CQ da Rocha, EF Queiroz, CS Meira, DRM Moreira, MBP Soares, ... Journal of natural products 77 (6), 1345-1350, 2014 | 70 | 2014 |
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death DRM Moreira, ADT de Oliveira, PAT de Moraes Gomes, CA de Simone, ... European journal of medicinal chemistry 75, 467-478, 2014 | 69 | 2014 |
Ruthenium (II) complexes of 1, 3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole RS Corrêa, MM da Silva, AE Graminha, CS Meira, JAF Dos Santos, ... Journal of inorganic biochemistry 156, 153-163, 2016 | 68 | 2016 |
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents MZ Hernandes, MM Rabello, ACL Leite, MVO Cardoso, DRM Moreira, ... Bioorganic & Medicinal Chemistry 18 (22), 7826-7835, 2010 | 68 | 2010 |
Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma Cruzi Cruzain JWP Espíndola, MV de Oliveira Cardoso, GB de Oliveira Filho, ... European Journal of Medicinal Chemistry 101, 818-835, 2015 | 66 | 2015 |
Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation AR Bastian, A Nangarlia, LD Bailey, A Holmes, RVK Sundaram, C Ang, ... Journal of Biological Chemistry 290 (1), 529-543, 2015 | 62 | 2015 |
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles EF Santiago, SA de Oliveira, GB de Oliveira Filho, DRM Moreira, ... Antimicrobial agents and chemotherapy 58 (1), 352-363, 2014 | 62 | 2014 |
New 1, 3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi PAT de Moraes Gomes, M de Oliveira Barbosa, EF Santiago, ... European Journal of Medicinal Chemistry 121, 387-398, 2016 | 61 | 2016 |
Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi EF Silva-Júnior, EPS Silva, PHB França, JPN Silva, EO Barreto, EB Silva, ... Bioorganic & medicinal chemistry 24 (18), 4228-4240, 2016 | 61 | 2016 |
Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi GB de Oliveira Filho, MV de Oliveira Cardoso, JWP Espíndola, ... European Journal of Medicinal Chemistry 141, 346-361, 2017 | 58 | 2017 |