Michele Tavecchio
Michele Tavecchio
Senior Scientist, NeuroVive Pharmaceutical SA
Verified email at
Cited by
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Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells
G Germano, R Frapolli, M Simone, M Tavecchio, E Erba, S Pesce, ...
Cancer research 70 (6), 2235-2244, 2010
Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors
C Forni, M Minuzzo, E Virdis, E Tamborini, M Simone, M Tavecchio, ...
Molecular cancer therapeutics 8 (2), 449-457, 2009
DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin
WM Ciszewski, M Tavecchio, J Dastych, NJ Curtin
Breast cancer research and treatment 143, 47-55, 2014
The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo
D Brunelli, M Tavecchio, C Falcioni, R Frapolli, E Erba, R Iori, P Rollin, ...
Biochemical pharmacology 79 (8), 1141-1148, 2010
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K
JM Munck, MA Batey, Y Zhao, H Jenkins, CJ Richardson, C Cano, ...
Molecular cancer therapeutics 11 (8), 1789-1798, 2012
Role of homologous recombination in trabectedin-induced DNA damage
M Tavecchio, M Simone, E Erba, I Chiolo, G Liberi, M Foiani, M D’Incalci, ...
European Journal of Cancer 44 (4), 609-618, 2008
Adaptive mitochondrial reprogramming and resistance to PI3K therapy
JC Ghosh, MD Siegelin, V Vaira, A Faversani, M Tavecchio, YC Chae, ...
Journal of the National Cancer Institute 107 (3), dju502, 2015
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α
S Basu, K Gnanapradeepan, T Barnoud, CP Kung, M Tavecchio, J Scott, ...
Genes & development 32 (3-4), 230-243, 2018
Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination
M Tavecchio, JM Munck, C Cano, DR Newell, NJ Curtin
Cancer chemotherapy and pharmacology 69, 155-164, 2012
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
BH Kang, M Tavecchio, HL Goel, CC Hsieh, DS Garlick, CM Raskett, ...
British journal of cancer 104 (4), 629-634, 2011
Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
S Lisanti, M Tavecchio, YC Chae, Q Liu, AK Brice, ML Thakur, ...
Cell Reports 8 (3), 671-677, 2014
Cyclophilin D Extramitochondrial Signaling Controls Cell Cycle Progression and Chemokine-directed Cell Motility*[S]
M Tavecchio, S Lisanti, A Lam, JC Ghosh, NM Martin, M O'Connell, ...
Journal of Biological Chemistry 288 (8), 5553-5561, 2013
Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil
M Ganzinelli, L Carrassa, F Crippa, M Tavecchio, M Broggini, G Damia
Clinical Cancer Research 14 (16), 5131-5141, 2008
Deletion of cyclophilin D impairs β-oxidation and promotes glucose metabolism
M Tavecchio, S Lisanti, MJ Bennett, LR Languino, DC Altieri
Scientific reports 5 (1), 15981, 2015
Antitumor activity of the retinoid-related molecules (E)-3-(4′-hydroxy-3′-adamantylbiphenyl-4-yl) acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene …
E Parrella, M Gianń, M Fratelli, MM Barzago, I Raska, L Diomede, ...
Molecular pharmacology 70 (3), 909-924, 2006
Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity
C Valli, G Paroni, AM Di Francesco, R Riccardi, M Tavecchio, E Erba, ...
Molecular cancer therapeutics 7 (9), 2941-2954, 2008
Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development
S Lisanti, DS Garlick, KG Bryant, M Tavecchio, GB Mills, Y Lu, ...
Journal of Biological Chemistry 291 (48), 25247-25254, 2016
Dynamics of cell cycle phase perturbations by trabectedin (ET‐743) in nucleotide excision repair (NER)‐deficient and NER‐proficient cells, unravelled by a novel mathematical …
M Tavecchio, C Natoli, P Ubezio, E Erba, M D’Incalci
Cell proliferation 40 (6), 885-904, 2007
Chk2 phosphorylation of survivin-ΔEx3 contributes to a DNA damage–sensing checkpoint in cancer
A Lopergolo, M Tavecchio, S Lisanti, JC Ghosh, T Dohi, A Faversani, ...
Cancer research 72 (13), 3251-3259, 2012
Multi-parametric flow cytometric cell cycle analysis using TO-PRO-3 iodide (TP3): detailed protocols
M Tavecchio, M Simone, S Bernasconi, G Tognon, G Mazzini, E Erba
Acta histochemica 110 (3), 232-244, 2008
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