Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 246 | 2013 |
Endochin Optimization: Structure−Activity and Structure−Property Relationship Studies of 3-Substituted 2-Methyl-4(1H)-quinolones with Antimalarial Activity RM Cross, A Monastyrskyi, TS Mutka, JN Burrows, DE Kyle, R Manetsch Journal of medicinal chemistry 53 (19), 7076-7094, 2010 | 138 | 2010 |
Epigenetic Tailoring for the Production of Anti-Infective Cytosporones from the Marine Fungus Leucostoma persoonii J Beau, N Mahid, WN Burda, L Harrington, LN Shaw, T Mutka, DE Kyle, ... Marine Drugs 10 (4), 762-774, 2012 | 123 | 2012 |
Phenotypic and Genotypic Analysis of In Vitro-Selected Artemisinin-Resistant Progeny of Plasmodium falciparum MS Tucker, T Mutka, K Sparks, J Patel, DE Kyle Antimicrobial agents and chemotherapy 56 (1), 302-314, 2012 | 105 | 2012 |
Optimization of 1, 2, 3, 4-tetrahydroacridin-9 (10H)-ones as antimalarials utilizing structure–activity and structure–property relationships RM Cross, JR Maignan, TS Mutka, L Luong, J Sargent, DE Kyle, ... American Chemical Society, 2011 | 83 | 2011 |
Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta CL Shao, RG Linington, MJ Balunas, A Centeno, P Boudreau, C Zhang, ... The Journal of Organic Chemistry 80 (16), 7849-7855, 2015 | 77 | 2015 |
Screening mangrove endophytic fungi for antimalarial natural products L Calcul, C Waterman, WS Ma, MD Lebar, C Harter, T Mutka, L Morton, ... Marine drugs 11 (12), 5036-5050, 2013 | 76 | 2013 |
Synthesis, Antimalarial Activity, and Structure–Activity Relationship of 7-(2-Phenoxyethoxy)-4(1H)-quinolones RM Cross, NK Namelikonda, TS Mutka, L Luong, DE Kyle, R Manetsch Journal of medicinal chemistry 54 (24), 8321-8327, 2011 | 71 | 2011 |
Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium RM Cross, DL Flanigan, A Monastyrskyi, AN LaCrue, FE Sáenz, ... Journal of Medicinal Chemistry 57 (21), 8860-8879, 2014 | 42 | 2014 |
4(1H)-Quinolones with Liver Stage Activity against Plasmodium berghei AN LaCrue, FE Sáenz, RM Cross, KO Udenze, A Monastyrskyi, S Stein, ... Antimicrobial agents and chemotherapy 57 (1), 417-424, 2013 | 42 | 2013 |
Novel 4-Aminoquinoline Analogs Highly Active against the Blood and Sexual Stages of Plasmodium In Vivo and In Vitro FE Sáenz, T Mutka, K Udenze, AMJ Oduola, DE Kyle Antimicrobial agents and chemotherapy 56 (9), 4685-4692, 2012 | 41 | 2012 |
Norselic Acids A−E, Highly Oxidized Anti-infective Steroids that Deter Mesograzer Predation, from the Antarctic Sponge Crella sp. WS Ma, T Mutka, B Vesley, MO Amsler, JB McClintock, CD Amsler, ... Journal of natural products 72 (10), 1842-1846, 2009 | 40 | 2009 |
CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs MD Lebar, KN Hahn, T Mutka, P Maignan, JB McClintock, CD Amsler, ... Bioorganic & medicinal chemistry 19 (19), 5756-5762, 2011 | 39 | 2011 |
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property … R Neelarapu, JR Maignan, CL Lichorowic, A Monastyrskyi, TS Mutka, ... Journal of medicinal chemistry 61 (4), 1450-1473, 2018 | 32 | 2018 |
ICI 56,780 Optimization: Structure–Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity JR Maignan, CL Lichorowic, J Giarrusso, LD Blake, D Casandra, ... Journal of medicinal chemistry 59 (14), 6943-6960, 2016 | 26 | 2016 |
Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med 5: 177ra37 A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... | 19 | 2013 |
Transition-metal-free one-pot tandem synthesis of 4-quinolone and 4H-thiochromen-4-one derivatives through sequential nucleophilic addition–elimination–SNAr reaction D Wang, P Sun, P Jia, J Peng, Y Yue, C Chen Synthesis 49 (18), 4309-4320, 2017 | 18 | 2017 |
Synthesis and activity of a new series of antileishmanial agents A Kanwar, BJ Eduful, L Barbeto, P Carletti Bonomo, A Lemus, BA Vesely, ... ACS Medicinal Chemistry Letters 8 (8), 797-801, 2017 | 13 | 2017 |
Miniaturized cultivation of microbiota for antimalarial drug discovery C Waterman, L Calcul, J Beau, WS Ma, MD Lebar, JL von Salm, C Harter, ... Medicinal Research Reviews 36 (1), 144-168, 2016 | 9 | 2016 |
A potent antimalarial trichothecene from hyphomycete species C Waterman, L Calcul, T Mutka, DE Kyle, CJ Pearce, BJ Baker Tetrahedron letters 55 (29), 3989-3991, 2014 | 8 | 2014 |