Model of chemotherapy-induced myelosuppression with parameter consistency across drugs LE Friberg, A Henningsson, H Maas, L Nguyen, MO Karlsson Journal of clinical oncology 20 (24), 4713-4721, 2002 | 659 | 2002 |
Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gram … D Plachouras, M Karvanen, LE Friberg, E Papadomichelakis, ... Antimicrobial agents and chemotherapy 53 (8), 3430-3436, 2009 | 629 | 2009 |
Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial M Paul, GL Daikos, E Durante-Mangoni, D Yahav, Y Carmeli, YD Benattar, ... The lancet Infectious diseases 18 (4), 391-400, 2018 | 565 | 2018 |
Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs EI Nielsen, LE Friberg Pharmacological reviews 65 (3), 1053-1090, 2013 | 356 | 2013 |
Application of a loading dose of colistin methanesulfonate in critically ill patients: population pharmacokinetics, protein binding, and prediction of bacterial kill AF Mohamed, I Karaiskos, D Plachouras, M Karvanen, K Pontikis, ... Antimicrobial agents and chemotherapy 56 (8), 4241-4249, 2012 | 311 | 2012 |
Systematic Review and Meta-Analysis of In Vitro Synergy of Polymyxins and Carbapenems O Zusman, T Avni, L Leibovici, A Adler, L Friberg, T Stergiopoulou, ... Antimicrobial agents and chemotherapy 57 (10), 5104-5111, 2013 | 298 | 2013 |
Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization EI Nielsen, O Cars, LE Friberg Antimicrobial agents and chemotherapy 55 (10), 4619-4630, 2011 | 280 | 2011 |
A review of mixed‐effects models of tumor growth and effects of anticancer drug treatment used in population analysis B Ribba, NH Holford, P Magni, I Trocóniz, I Gueorguieva, P Girard, C Sarr, ... CPT: pharmacometrics & systems pharmacology 3 (5), 1-10, 2014 | 209 | 2014 |
Irinotecan‐induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein FA De Jong, TJ Scott‐Horton, DL Kroetz, HL McLeod, LE Friberg, ... Clinical Pharmacology & Therapeutics 81 (1), 42-49, 2007 | 200 | 2007 |
Integrated population pharmacokinetic analysis of voriconazole in children, adolescents, and adults LE Friberg, P Ravva, MO Karlsson, P Liu Antimicrobial agents and chemotherapy 56 (6), 3032-3042, 2012 | 180 | 2012 |
From therapeutic drug monitoring to model‐informed precision dosing for antibiotics SG Wicha, AG Märtson, EI Nielsen, BCP Koch, LE Friberg, JW Alffenaar, ... Clinical Pharmacology & Therapeutics 109 (4), 928-941, 2021 | 174 | 2021 |
Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia JM Van der Bol, RHJ Mathijssen, WJ Loos, LE Friberg, RHN van Schaik, ... Journal of Clinical Oncology 25 (19), 2719-2726, 2007 | 157 | 2007 |
Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes RHJ Mathijssen, FA de Jong, RHN van Schaik, ER Lepper, LE Friberg, ... Journal of the National Cancer Institute 96 (21), 1585-1592, 2004 | 147 | 2004 |
Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MS B Jansson, M Karvanen, O Cars, D Plachouras, LE Friberg Journal of pharmaceutical and biomedical analysis 49 (3), 760-767, 2009 | 133 | 2009 |
The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections T Tängdén, V Ramos Martín, TW Felton, EI Nielsen, S Marchand, ... Intensive care medicine 43, 1021-1032, 2017 | 132 | 2017 |
Colistin population pharmacokinetics after application of a loading dose of 9 MU colistin methanesulfonate in critically ill patients I Karaiskos, LE Friberg, K Pontikis, K Ioannidis, V Tsagkari, L Galani, ... Antimicrobial agents and chemotherapy 59 (12), 7240-7248, 2015 | 132 | 2015 |
Impact of CYP2C8* 3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer TK Bergmann, C Brasch-Andersen, H Green, M Mirza, RS Pedersen, ... The pharmacogenomics journal 11 (2), 113-120, 2011 | 128 | 2011 |
Mechanistic models for myelosuppression LE Friberg, MO Karlsson Investigational new drugs 21, 183-194, 2003 | 128 | 2003 |
A long-term prospective population pharmacokinetic study on imatinib plasma concentrations in GIST patients K Eechoute, MN Fransson, AK Reyners, FA De Jong, A Sparreboom, ... Clinical Cancer Research 18 (20), 5780-5787, 2012 | 124 | 2012 |
Colistin Is Extensively Lost during Standard In Vitro Experimental Conditions M Karvanen, C Malmberg, P Lagerbäck, LE Friberg, O Cars Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 00857-17, 2017 | 117 | 2017 |