Mark A Saper, Ph.D.
Mark A Saper, Ph.D.
Dept of Biological Chemistry, University of Michigan
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Structure of the human class I histocompatibility antigen, HLA-A2
PJ Bjorkman, MA Saper, B Samraoui, WS Bennett, JL Strominger, ...
Nature 329 (6139), 506-512, 1987
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
PJ Bjorkman, MA Saper, B Samraoui, WS Bennett, JL Strominger, ...
Nature 329 (6139), 512-518, 1987
A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules
JH Brown, T Jardetzky, MA Saper, B Samraoui, PJ Bjorkman, DC Wiley
Nature 332 (6167), 845-850, 1988
Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 resolution
MA Saper, PJ Bjorkman, DC Wiley
Journal of molecular biology 219 (2), 277-319, 1991
Specificity pockets for the side chains of peptide antigens in HLA-Aw68
TPJ Garrett, MA Saper, PJ Bjorkman, JL Strominger, DC Wiley
Nature 342 (6250), 692-696, 1989
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 and the complex with tungstate
JA Stuckey, HL Schubert, EB Fauman, ZY Zhang, JE Dixon, MA Saper
Nature 370 (6490), 571-575, 1994
Form and function in protein dephosphorylation
JM Denu, JA Stuckey, MA Saper, JE Dixon
Cell 87 (3), 361-364, 1996
Structure and function of the protein tyrosine phosphatases
EB Fauman, MA Saper
Trends in biochemical sciences 21 (11), 413-417, 1996
Crystal structure of the dual specificity protein phosphatase VHR
J Yuvaniyama, JM Denu, JE Dixon, MA Saper
Science 272 (5266), 1328-1331, 1996
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
EB Fauman, JP Cogswell, B Lovejoy, WJ Rocque, W Holmes, ...
Cell 93 (4), 617-625, 1998
Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis.
JM Denu, DL Lohse, J Vijayalakshmi, MA Saper, JE Dixon
Proceedings of the National Academy of Sciences 93 (6), 2493-2498, 1996
Periplasmic binding protein structure and function: Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine
JS Sack, MA Saper, FA Quiocho
Journal of molecular biology 206 (1), 171-191, 1989
RNA methylation under heat shock control
H Bgl, EB Fauman, BL Staker, F Zheng, SR Kushner, MA Saper, ...
Molecular cell 6 (2), 349-360, 2000
Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.
ZY Zhang, JC Clemens, HL Schubert, JA Stuckey, MW Fischer, DM Hume, ...
Journal of Biological Chemistry 267 (33), 23759-23766, 1992
The Cys (X)5 Arg catalytic motif in phosphoester hydrolysis
ZY Zhang, Y Wang, L Wu, EB Fauman, JA Stuckey, HL Schubert, ...
Biochemistry 33 (51), 15266-15270, 1994
Evidence that multiple residues on both the α-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor
P Ajitkumar, SS Geier, KV Kesari, F Borriello, M Nakagawa, JA Bluestone, ...
Cell 54 (1), 47-56, 1988
Activation of the redox-regulated molecular chaperone Hsp33—a two-step mechanism
J Graumann, H Lilie, X Tang, KA Tucker, JH Hoffmann, J Vijayalakshmi, ...
Structure 9 (5), 377-387, 2001
The Purification and Characterization of a Human Dual-specific Protein Tyrosine Phosphatase (∗)
JM Denu, G Zhou, L Wu, R Zhao, J Yuvaniyama, MA Saper, JE Dixon
Journal of Biological Chemistry 270 (8), 3796-3803, 1995
A ligand‐induced conformational change in the yersinia protein tyrosine phosphatase
HL Schubert, EB Fauman, JA Stuckey, JE Dixon, MA Saper
Protein Science 4 (9), 1904-1913, 1995
The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate: mechanistic implications
EB Fauman, C Yuvaniyama, HL Schubert, JA Stuckey, MA Saper
Journal of Biological Chemistry 271 (31), 18780-18788, 1996
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