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Andrey Loboda
Andrey Loboda
Director, Computational and Systems Biology, Merck
Verified email at merck.com
Title
Cited by
Cited by
Year
IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
M Ayers, J Lunceford, M Nebozhyn, E Murphy, A Loboda, DR Kaufman, ...
The Journal of clinical investigation 127 (8), 2930-2940, 2017
28542017
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
R Cristescu, J Lee, M Nebozhyn, KM Kim, JC Ting, SS Wong, J Liu, ...
Nature medicine 21 (5), 449-456, 2015
18172015
Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy
R Cristescu, R Mogg, M Ayers, A Albright, E Murphy, J Yearley, X Sher, ...
Science 362 (6411), eaar3593, 2018
17912018
Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer
ST Kim, R Cristescu, AJ Bass, KM Kim, JI Odegaard, K Kim, XQ Liu, ...
Nature medicine 24 (9), 1449-1458, 2018
12282018
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
Z Kan, H Zheng, X Liu, S Li, TD Barber, Z Gong, H Gao, K Hao, ...
Genome research 23 (9), 1422-1433, 2013
5562013
Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors
V Kumar, L Donthireddy, D Marvel, T Condamine, F Wang, ...
Cancer cell 32 (5), 654-668. e5, 2017
5392017
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes
G Garcia-Manero, H Yang, C Bueso-Ramos, A Ferrajoli, J Cortes, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1060-1066, 2008
5292008
Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study
E Galanis, KA Jaeckle, MJ Maurer, JM Reid, MM Ames, JS Hardwick, ...
Journal of clinical oncology 27 (12), 2052, 2009
4012009
Analysis of genomic targets reveals complex functions of MYC
JH Patel, AP Loboda, MK Showe, LC Showe, SB McMahon
Nature Reviews Cancer 4 (7), 562-568, 2004
3802004
Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors
I Krop, T Demuth, T Guthrie, PY Wen, WP Mason, P Chinnaiyan, ...
Journal of clinical oncology 30 (19), 2307-2313, 2012
3432012
Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling
D Coppola, M Nebozhyn, F Khalil, H Dai, T Yeatman, A Loboda, JJ Mulé
The American journal of pathology 179 (1), 37-45, 2011
3232011
EMT is the dominant program in human colon cancer
A Loboda, MV Nebozhyn, JW Watters, CA Buser, PM Shaw, PS Huang, ...
BMC medical genomics 4, 1-10, 2011
3202011
Functional genomics identifies therapeutic targets for MYC-driven cancer
M Toyoshima, HL Howie, M Imakura, RM Walsh, JE Annis, AN Chang, ...
Proceedings of the National Academy of Sciences 109 (24), 9545-9550, 2012
2912012
An unbiased oncology compound screen to identify novel combination strategies
J O'Neil, Y Benita, I Feldman, M Chenard, B Roberts, Y Liu, J Li, A Kral, ...
Molecular cancer therapeutics 15 (6), 1155-1162, 2016
2612016
Transcriptional architecture of the primate neocortex
A Bernard, LS Lubbers, KQ Tanis, R Luo, AA Podtelezhnikov, EM Finney, ...
Neuron 73 (6), 1083-1099, 2012
2462012
Association of response to programmed death receptor 1 (PD-1) blockade with pembrolizumab (MK-3475) with an interferon-inflammatory immune gene signature.
A Ribas, C Robert, FS Hodi, JD Wolchok, AM Joshua, WJ Hwu, JS Weber, ...
Journal of Clinical Oncology 33 (15_suppl), 3001-3001, 2015
2422015
Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma
L Kari, A Loboda, M Nebozhyn, AH Rook, EC Vonderheid, C Nichols, ...
The Journal of experimental medicine 197 (11), 1477-1488, 2003
2362003
A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC
MJ Schell, M Yang, JK Teer, FY Lo, A Madan, D Coppola, ANA Monteiro, ...
Nature communications 7 (1), 11743, 2016
2072016
Comparative expression pathway analysis of human and canine mammary tumors
P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni, J Castle, ...
BMC genomics 10, 1-20, 2009
2012009
Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma
VR Fantin, A Loboda, CP Paweletz, RC Hendrickson, JW Pierce, JA Roth, ...
Cancer research 68 (10), 3785-3794, 2008
1992008
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