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Wayne M Patrick
Wayne M Patrick
Associate Professor, School of Biological Sciences, Victoria University of Wellington
Verified email at vuw.ac.nz - Homepage
Title
Cited by
Cited by
Year
Novel methods for directed evolution of enzymes: quality, not quantity
S Lutz, WM Patrick
Current Opinion in Biotechnology 15 (4), 291-297, 2004
2812004
User‐friendly algorithms for estimating completeness and diversity in randomized protein‐encoding libraries
WM Patrick, AE Firth, JM Blackburn
Protein Engineering 16 (6), 451-457, 2003
2492003
Bacterial methionine biosynthesis
MP Ferla, WM Patrick
Microbiology 160 (8), 1571-1584, 2014
2452014
Multicopy suppression underpins metabolic evolvability
WM Patrick, EM Quandt, DB Swartzlander, I Matsumura
Molecular Biology and Evolution 24 (12), 2716-2722, 2007
2032007
Mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa: new approaches to an old problem
A Rehman, WM Patrick, IL Lamont
Journal of Medical Microbiology 68 (1), 1-10, 2019
1822019
GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries
AE Firth, WM Patrick
Nucleic acids research 36 (suppl_2), W281-W285, 2008
1622008
Strategies and computational tools for improving randomized protein libraries
WM Patrick, AE Firth
Biomolecular engineering 22 (4), 105-112, 2005
1462005
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli
VWC Soo, P Hanson-Manful, WM Patrick
Proceedings of the National Academy of Sciences 108 (4), 1484-1489, 2011
1332011
New rRNA gene-based phylogenies of the Alphaproteobacteria provide perspective on major groups, mitochondrial ancestry and phylogenetic instability
MP Ferla, JC Thrash, SJ Giovannoni, WM Patrick
PloS One 8 (12), e83383, 2013
1312013
Statistics of protein library construction
AE Firth, WM Patrick
Bioinformatics 21 (15), 3314-3315, 2005
1172005
Reconstruction of an acetogenic 2, 3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase
M Köpke, ML Gerth, DJ Maddock, AP Mueller, FM Liew, SD Simpson, ...
Applied and environmental microbiology 80 (11), 3394-3403, 2014
1062014
Enzyme evolution: innovation is easy, optimization is complicated
MS Newton, VL Arcus, ML Gerth, WM Patrick
Current Opinion in Structural Biology 48, 110-116, 2018
952018
Natural history as a predictor of protein evolvability
TL O'Loughlin, WM Patrick, I Matsumura
Protein Engineering, Design and Selection 19 (10), 439-442, 2006
822006
A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase
WM Patrick, I Matsumura
Journal of molecular biology 377 (2), 323-336, 2008
642008
Error-prone PCR and effective generation of gene variant libraries for directed evolution
JN Copp, P Hanson-Manful, DF Ackerley, WM Patrick
Directed Evolution Library Creation: Methods and Protocols, 3-22, 2014
612014
A second-generation system for unbiased reading frame selection
ML Gerth, WM Patrick, S Lutz
Protein Engineering Design and Selection 17 (7), 595-602, 2004
532004
The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators
DCC Wai, TN Szyszka, AE Campbell, C Kwong, LE Wilkinson-White, ...
Journal of Biological Chemistry 293 (19), 7160-7175, 2018
502018
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
KA Davies, C Fitzgibbon, SN Young, SE Garnish, W Yeung, D Coursier, ...
Nature Communications 11 (1), 3060, 2020
482020
Mātauranga-guided screening of New Zealand native plants reveals flavonoids from kānuka (Kunzea robusta) with anti-Phytophthora activity
SA Lawrence, EJ Burgess, C Pairama, A Black, WM Patrick, I Mitchell, ...
Journal of the Royal Society of new Zealand 49 (sup1), 137-154, 2019
472019
Construction and analysis of randomized protein-encoding libraries using error-prone PCR
P Hanson-Manful, WM Patrick
Protein Nanotechnology: Protocols, Instrumentation, and Applications, Second …, 2013
422013
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