| Novel methods for directed evolution of enzymes: quality, not quantity S Lutz, WM Patrick Current Opinion in Biotechnology 15 (4), 291-297, 2004 | 283 | 2004 |
| Bacterial methionine biosynthesis MP Ferla, WM Patrick Microbiology 160 (8), 1571-1584, 2014 | 255 | 2014 |
| User‐friendly algorithms for estimating completeness and diversity in randomized protein‐encoding libraries WM Patrick, AE Firth, JM Blackburn Protein Engineering 16 (6), 451-457, 2003 | 255 | 2003 |
| Multicopy suppression underpins metabolic evolvability WM Patrick, EM Quandt, DB Swartzlander, I Matsumura Molecular Biology and Evolution 24 (12), 2716-2722, 2007 | 208 | 2007 |
| Mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa: new approaches to an old problem A Rehman, WM Patrick, IL Lamont Journal of Medical Microbiology 68 (1), 1-10, 2019 | 200 | 2019 |
| GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries AE Firth, WM Patrick Nucleic acids research 36 (suppl_2), W281-W285, 2008 | 164 | 2008 |
| Strategies and computational tools for improving randomized protein libraries WM Patrick, AE Firth Biomolecular engineering 22 (4), 105-112, 2005 | 148 | 2005 |
| Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli VWC Soo, P Hanson-Manful, WM Patrick Proceedings of the National Academy of Sciences 108 (4), 1484-1489, 2011 | 136 | 2011 |
| New rRNA gene-based phylogenies of the Alphaproteobacteria provide perspective on major groups, mitochondrial ancestry and phylogenetic instability MP Ferla, JC Thrash, SJ Giovannoni, WM Patrick PloS One 8 (12), e83383, 2013 | 135 | 2013 |
| Statistics of protein library construction AE Firth, WM Patrick Bioinformatics 21 (15), 3314-3315, 2005 | 119 | 2005 |
| Reconstruction of an acetogenic 2, 3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase M Köpke, ML Gerth, DJ Maddock, AP Mueller, FM Liew, SD Simpson, ... Applied and environmental microbiology 80 (11), 3394-3403, 2014 | 109 | 2014 |
| Enzyme evolution: innovation is easy, optimization is complicated MS Newton, VL Arcus, ML Gerth, WM Patrick Current Opinion in Structural Biology 48, 110-116, 2018 | 97 | 2018 |
| Natural history as a predictor of protein evolvability TL O'Loughlin, WM Patrick, I Matsumura Protein Engineering, Design and Selection 19 (10), 439-442, 2006 | 83 | 2006 |
| A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase WM Patrick, I Matsumura Journal of molecular biology 377 (2), 323-336, 2008 | 65 | 2008 |
| Error-prone PCR and effective generation of gene variant libraries for directed evolution JN Copp, P Hanson-Manful, DF Ackerley, WM Patrick Directed Evolution Library Creation: Methods and Protocols, 3-22, 2014 | 63 | 2014 |
| Mātauranga-guided screening of New Zealand native plants reveals flavonoids from kānuka (Kunzea robusta) with anti-Phytophthora activity SA Lawrence, EJ Burgess, C Pairama, A Black, WM Patrick, I Mitchell, ... Journal of the Royal Society of new Zealand 49 (sup1), 137-154, 2019 | 53 | 2019 |
| A second-generation system for unbiased reading frame selection ML Gerth, WM Patrick, S Lutz Protein Engineering Design and Selection 17 (7), 595-602, 2004 | 53 | 2004 |
| The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators DCC Wai, TN Szyszka, AE Campbell, C Kwong, LE Wilkinson-White, ... Journal of Biological Chemistry 293 (19), 7160-7175, 2018 | 52 | 2018 |
| Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues KA Davies, C Fitzgibbon, SN Young, SE Garnish, W Yeung, D Coursier, ... Nature communications 11 (1), 3060, 2020 | 50 | 2020 |
| A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas aeruginosa SJT Wardell, A Rehman, LW Martin, C Winstanley, WM Patrick, IL Lamont Antimicrobial agents and chemotherapy 63 (12), 10.1128/aac. 01619-19, 2019 | 42 | 2019 |
Monica L. GerthVictoria University of WellingtonVerified email at vuw.ac.nz
