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Chandrasekhar Natarajan
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Predictable convergence in hemoglobin function has unpredictable molecular underpinnings
C Natarajan, FG Hoffmann, RE Weber, A Fago, CC Witt, JF Storz
Science 354 (6310), 336-339, 2016
2522016
Epistasis Among Adaptive Mutations in Deer Mouse Hemoglobin
C Natarajan, N Inoguchi, RE Weber, A Fago, H Moriyama, JF Storz
Science 340 (6138), 1324-1327, 2013
2042013
Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds
J Projecto-Garcia, C Natarajan, H Moriyama, RE Weber, A Fago, ...
Proceedings of the National Academy of Sciences 110 (51), 20669-20674, 2013
1982013
Convergent evolution of hemoglobin function in high-altitude Andean waterfowl involves limited parallelism at the molecular sequence level
C Natarajan, J Projecto-Garcia, H Moriyama, RE Weber, ...
PLoS genetics 11 (12), e1005681, 2015
1242015
Epistasis constrains mutational pathways of hemoglobin adaptation in high-altitude pikas
DM Tufts, C Natarajan, IG Revsbech, J Projecto-Garcia, FG Hoffmann, ...
Molecular biology and evolution 32 (2), 287-298, 2015
1152015
Intraspecific polymorphism, interspecific divergence, and the origins of function-altering mutations in deer mouse hemoglobin
C Natarajan, FG Hoffmann, HC Lanier, CJ Wolf, ZA Cheviron, ...
Molecular biology and evolution 32 (4), 978-997, 2015
1022015
Contribution of a mutational hot spot to hemoglobin adaptation in high-altitude Andean house wrens
SC Galen, C Natarajan, H Moriyama, RE Weber, A Fago, PM Benham, ...
Proceedings of the National Academy of Sciences 112 (45), 13958-13963, 2015
1012015
Divergent and parallel routes of biochemical adaptation in high-altitude passerine birds from the Qinghai-Tibet Plateau
X Zhu, Y Guan, AV Signore, C Natarajan, SG DuBay, Y Cheng, N Han, ...
Proceedings of the National Academy of Sciences 115 (8), 1865-1870, 2018
922018
Molecular basis of hemoglobin adaptation in the high-flying bar-headed goose
C Natarajan, A Jendroszek, A Kumar, RE Weber, JRH Tame, A Fago, ...
PLoS genetics 14 (4), e1007331, 2018
692018
Gene duplication and the evolution of hemoglobin isoform differentiation in birds
MT Grispo, C Natarajan, J Projecto-Garcia, H Moriyama, RE Weber, ...
Journal of Biological Chemistry 287 (45), 37647-37658, 2012
692012
Integrating evolutionary and functional tests of adaptive hypotheses: a case study of altitudinal differentiation in hemoglobin function in an Andean sparrow, Zonotrichia capensis
ZA Cheviron, C Natarajan, J Projecto-Garcia, DK Eddy, J Jones, ...
Molecular Biology and Evolution 31 (11), 2948-2962, 2014
682014
Expression and purification of recombinant hemoglobin in Escherichia coli
C Natarajan, X Jiang, A Fago, RE Weber, H Moriyama, JF Storz
PLoS One 6 (5), e20176, 2011
672011
Association of dopamine receptor polymorphisms with schizophrenia and antipsychotic response in a South Indian population
NN Vijayan, S Bhaskaran, LV Koshy, C Natarajan, L Srinivas, CM Nair, ...
Behav Brain Funct 3, 34, 2007
662007
Stability-mediated epistasis restricts accessible mutational pathways in the functional evolution of avian hemoglobin
A Kumar, C Natarajan, H Moriyama, CC Witt, RE Weber, A Fago, JF Storz
Molecular Biology and Evolution 34 (5), 1240-1251, 2017
582017
Gene turnover in the avian globin gene families and evolutionary changes in hemoglobin isoform expression
JC Opazo, FG Hoffmann, C Natarajan, CC Witt, M Berenbrink, JF Storz
Molecular biology and evolution 32 (4), 871-887, 2015
532015
The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function
JF Storz, C Natarajan, AV Signore, CC Witt, DM McCandlish, A Stoltzfus
Philosophical Transactions of the Royal Society B 374 (1777), 20180238, 2019
452019
Altitudinal variation at duplicated β-globin genes in deer mice: effects of selection, recombination, and gene conversion
JF Storz, C Natarajan, ZA Cheviron, FG Hoffmann, JK Kelly
Genetics 190 (1), 203-216, 2012
452012
Evidence of association of serotonin transporter gene polymorphisms with schizophrenia in a South Indian population
NN Vijayan, Y Iwayama, LV Koshy, C Natarajan, C Nair, PM Allencherry, ...
Journal of human genetics 54 (9), 538-542, 2009
442009
Antipsychotic drug dosage and therapeutic response in schizophrenia is influenced by ABCB1 genotypes: a study from a south Indian perspective
NN Vijayan, A Mathew, S Balan, C Natarajan, CM Nair, PM Allencherry, ...
Pharmacogenomics 13 (10), 1119-1127, 2012
372012
Allosteric mechanisms underlying the adaptive increase in hemoglobin–oxygen affinity of the bar-headed goose
A Jendroszek, H Malte, CB Overgaard, K Beedholm, C Natarajan, ...
Journal of Experimental Biology 221 (18), jeb185470, 2018
362018
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