| p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells. L Tuosto, F Michel, O Acuto The Journal of experimental medicine 184 (3), 1161-1166, 1996 | 241 | 1996 |
| CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse R Tavano, RL Contento, SJ Baranda, M Soligo, L Tuosto, S Manes, ... Nature cell biology 8 (11), 1270-1276, 2006 | 211 | 2006 |
| Organization of plasma membrane functional rafts upon T cell activation L Tuosto, I Parolini, S Schröder, M Sargiacomo, A Lanzavecchia, A Viola European journal of immunology 31 (2), 345-349, 2001 | 194 | 2001 |
| T helper cells: the modulators of inflammation in multiple sclerosis M Kunkl, S Frascolla, C Amormino, E Volpe, L Tuosto Cells 9 (2), 482, 2020 | 188 | 2020 |
| CD28 affects the earliest signaling events generated by TCR engagement L Tuosto, O Acuto European journal of immunology 28 (7), 2131-2142, 1998 | 144 | 1998 |
| CD28 and lipid rafts coordinate recruitment of Lck to the immunological synapse of human T lymphocytes R Tavano, G Gri, B Molon, B Marinari, CE Rudd, L Tuosto, A Viola The Journal of Immunology 173 (9), 5392, 2004 | 135 | 2004 |
| CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation F Michel, G Mangino, G Attal-Bonnefoy, L Tuosto, A Alcover, A Roumier, ... The Journal of Immunology 165 (7), 3820, 2000 | 134 | 2000 |
| Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering A Viola, M Salio, L Tuosto, S Linkert, O Acuto, A Lanzavecchia The Journal of experimental medicine 186 (10), 1775, 1997 | 133 | 1997 |
| Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells F Michel, L Grimaud, L Tuosto, O Acuto Journal of Biological Chemistry 273 (48), 31932-31938, 1998 | 127 | 1998 |
| Analysis of susceptibility of mature human T lymphocytes to dexamethasone‐induced apoptosis L Tuosto, E Cundari, MSG Montani, E Piccolella European journal of immunology 24 (5), 1061-1065, 1994 | 124 | 1994 |
| Hypervariable region 1 variants act as TCR antagonists for hepatitis C virus-specific CD4+ T cells L Frasca, P Del Porto, L Tuosto, B Marinari, C Scottā, M Carbonari, ... The Journal of Immunology 163 (2), 650, 1999 | 123 | 1999 |
| CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-κB subunits on IL-8 and Bcl-xL gene promoters B Marinari, A Costanzo, V Marzano, E Piccolella, L Tuosto Proceedings of the National Academy of Sciences of the United States of …, 2004 | 120 | 2004 |
| Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways D Mege, V Di Bartolo, V Germain, L Tuosto, F Michel, O Acuto Journal of Biological Chemistry 271 (51), 32644-32652, 1996 | 100 | 1996 |
| Vav cooperates with CD28 to induce NF‐κB activation via a pathway involving Rac‐1 and mitogen‐activated kinase kinase 1 B Marinari, A Costanzo, A Viola, F Michel, G Mangino, O Acuto, M Levrero, ... European journal of immunology 32 (2), 447-456, 2002 | 94 | 2002 |
| Transglutaminase type II is involved in the pathogenesis of endotoxic shock L Falasca, MG Farrace, A Rinaldi, L Tuosto, G Melino, M Piacentini The Journal of Immunology 180 (4), 2616-2624, 2008 | 78 | 2008 |
| Vav-1 and the IKKα subunit of IκB kinase functionally associate to induce NF-κB activation in response to CD28 engagement E Piccolella, F Spadaro, C Ramoni, B Marinari, A Costanzo, M Levrero, ... The Journal of Immunology 170 (6), 2895-2903, 2003 | 73 | 2003 |
| CD28 costimulatory signals in T lymphocyte activation: Emerging functions beyond a qualitative and quantitative support to TCR signalling N Porciello, L Tuosto Cytokine & growth factor reviews 28, 11-19, 2016 | 68 | 2016 |
| Identification of a novel HLA-B27 subtype by restriction analysis of a cytotoxic gamma delta T cell clone P Del Porto, M D'Amato, MT Fiorillo, L Tuosto, E Piccolella, R Sorrentino The Journal of Immunology 153 (7), 3093, 1994 | 67 | 1994 |
| NF-κB family of transcription factors: biochemical players of CD28 co-stimulation L Tuosto Immunology letters 135 (1-2), 1-9, 2011 | 66 | 2011 |
| Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells M Muscolini, R Cianfrocca, A Sajeva, S Mozzetti, G Ferrandina, ... Molecular cancer therapeutics 7 (6), 1410, 2008 | 64 | 2008 |
Antonio CostanzoHumanitas UniversityVerified email at hunimed.eu
