Resveratrol improves health and survival of mice on a high-calorie diet JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ... Nature 444 (7117), 337-342, 2006 | 5449 | 2006 |
Reducing inappropriate polypharmacy: the process of deprescribing IA Scott, SN Hilmer, E Reeve, K Potter, D Le Couteur, D Rigby, D Gnjidic, ... JAMA internal medicine 175 (5), 827-834, 2015 | 1609 | 2015 |
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span KJ Pearson, JA Baur, KN Lewis, L Peshkin, NL Price, N Labinskyy, ... Cell metabolism 8 (2), 157-168, 2008 | 1394 | 2008 |
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, L Waite, MJ Seibel, ... Journal of clinical epidemiology 65 (9), 989-995, 2012 | 1352 | 2012 |
Aging biology and geriatric clinical pharmacology AJ McLean, DG Le Couteur Pharmacological reviews 56 (2), 163-184, 2004 | 1034 | 2004 |
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice SM Solon-Biet, AC McMahon, JWO Ballard, K Ruohonen, LE Wu, ... Cell metabolism 19 (3), 418-430, 2014 | 1026 | 2014 |
Loss of muscle strength, mass (sarcopenia), and quality (specific force) and its relationship with functional limitation and physical disability: the Concord Health and Ageing … NN Hairi, RG Cumming, V Naganathan, DJ Handelsman, DG Le Couteur, ... Journal of the American Geriatrics Society 58 (11), 2055-2062, 2010 | 632 | 2010 |
Medication withdrawal trials in people aged 65 years and older S Iyer, V Naganathan, AJ McLachlan, DG Le Couteur Drugs & aging 25 (12), 1021-1031, 2008 | 454 | 2008 |
Benzodiazepines and risk of hip fractures in older people RG Cumming, DG Le Couteur CNS drugs 17 (11), 825-837, 2003 | 433 | 2003 |
Are sirtuins viable targets for improving healthspan and lifespan? JA Baur, Z Ungvari, RK Minor, DG Le Couteur, R De Cabo Nature reviews Drug discovery 11 (6), 443-461, 2012 | 421 | 2012 |
Parkinson's disease, pesticides, and glutathione transferase polymorphisms A Menegon, PG Board, AC Blackburn, GD Mellick, DG Le Couteur The Lancet 352 (9137), 1344-1346, 1998 | 421 | 1998 |
Clinical pharmacology in the geriatric patient SN Hilmer, AJ McLachlan, DG Le Couteur Fundamental & clinical pharmacology 21 (3), 217-230, 2007 | 386 | 2007 |
The aging liver: drug clearance and an oxygen diffusion barrier hypothesis DG Le Couteur, AJ McLean Clinical pharmacokinetics 34 (5), 359-373, 1998 | 381 | 1998 |
High‐risk prescribing and incidence of frailty among older community‐dwelling men D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, RG Cumming, ... Clinical Pharmacology & Therapeutics 91 (3), 521-528, 2012 | 372 | 2012 |
A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 369 | 2014 |
Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis DG Le Couteur, J Doust, H Creasey, C Brayne Bmj 347, 2013 | 289 | 2013 |
T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells A Warren, DG Le Couteur, R Fraser, DG Bowen, GW McCaughan, ... Hepatology 44 (5), 1182-1190, 2006 | 288 | 2006 |
Pesticides and Parkinson's disease DG Le Couteur, AJ McLean, MC Taylor, BL Woodham, PG Board Biomedicine & pharmacotherapy 53 (3), 122-130, 1999 | 285 | 1999 |
Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control SM Solon-Biet, VC Cogger, T Pulpitel, D Wahl, X Clark, EE Bagley, ... Nature metabolism 1 (5), 532-545, 2019 | 280 | 2019 |
Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes D Gnjidic, DG Le Couteur, L Kouladjian, SN Hilmer Clinics in geriatric medicine 28 (2), 237-253, 2012 | 278 | 2012 |