Arjun Thapa
Arjun Thapa
Stem Cells Institute, University of Louisville
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Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway
A Thapa, SD Jett, EY Chi
ACS Chemical Neuroscience 7 (1), 56-68, 2016
Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures
A Thapa, ER Woo, EY Chi, MG Sharoar, HG Jin, SY Shin, IS Park
Biochemistry 50 (13), 2445-2455, 2011
Dietary modulation of oxidative stress in Alzheimer’s disease
A Thapa, NJ Carroll
International journal of molecular sciences 18 (7), 1583, 2017
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function
J Xu, L Morris, A Thapa, H Ma, S Michalakis, M Biel, W Baehr, ...
Journal of Neuroscience 33 (37), 14939-14948, 2013
The Nlrp3 inflammasome as a “rising star” in studies of normal and malignant hematopoiesis
MZ Ratajczak, K Bujko, M Cymer, A Thapa, M Adamiak, J Ratajczak, ...
Leukemia 34 (6), 1512-1523, 2020
Keampferol-3-O-rhamnoside abrogates amyloid beta toxicity by modulating monomers and remodeling oligomers and fibrils to non-toxic aggregates
MG Sharoar, A Thapa, M Shahnawaz, VS Ramasamy, ER Woo, SY Shin, ...
Journal of biomedical science 19, 1-13, 2012
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration
H Ma, A Thapa, L Morris, TM Redmond, W Baehr, XQ Ding
Proceedings of the National Academy of Sciences 111 (9), 3602-3607, 2014
Membrane-mediated neuroprotection by curcumin from amyloid-β-peptide-induced toxicity
A Thapa, BC Vernon, K De la Pena, G Soliz, HA Moreno, GP López, ...
Langmuir 29 (37), 11713-11723, 2013
Therapeutic Genome Editing for Myotonic Dystrophy Type 1 Using CRISPR/Cas9
XG Wang Y, Hao L, Wang H, Santostefano K, Thapa A, Cleary J, Li H, Guo X ...
Mol Ther. 26 (11), 2617-2630, 2018
Purification of inclusion body—forming peptides and proteins in soluble form by fusion to Escherichia coli thermostable proteins
A Thapa, M Shahnawaz, P Karki, G Raj Dahal, M Golam Sharoar, ...
Biotechniques 44 (6), 787-796, 2008
The Nlrp3 inflammasome orchestrates mobilization of bone marrow-residing stem cells into peripheral blood
AM Lenkiewicz, M Adamiak, A Thapa, K Bujko, D Pedziwiatr, ...
Stem Cell Reviews and Reports 15, 391-403, 2019
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency
A Thapa, L Morris, J Xu, H Ma, S Michalakis, M Biel, XQ Ding
Journal of Biological Chemistry 287 (22), 18018-18029, 2012
NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow
MZ Ratajczak, M Adamiak, A Thapa, K Bujko, K Brzezniakiewicz-Janus, ...
Leukemia 33 (4), 815-825, 2019
Stable activity of a deubiquitylating enzyme (Usp2-cc) in the presence of high concentrations of urea and its application to purify aggregation-prone peptides
M Shahnawaz, A Thapa, IS Park
Biochemical and biophysical research communications 359 (3), 801-805, 2007
Nlrp3 inflammasome signaling regulates the homing and engraftment of hematopoietic stem cells (HSPCs) by enhancing incorporation of CXCR4 receptor into membrane lipid rafts
M Adamiak, A Abdel-Latif, K Bujko, A Thapa, K Anusz, M Tracz, ...
Stem Cell Reviews and Reports 16, 954-967, 2020
cGMP/protein kinase G signaling suppresses inositol 1, 4, 5-trisphosphate receptor phosphorylation and promotes endoplasmic reticulum stress in photoreceptors of cyclic …
H Ma, MR Butler, A Thapa, J Belcher, F Yang, W Baehr, M Biel, ...
Journal of Biological Chemistry 290 (34), 20880-20892, 2015
Biflavonoids as potential small molecule therapeutics for Alzheimer’s disease
A Thapa, EY Chi
Natural compounds as therapeutic agents for amyloidogenic diseases, 55-77, 2015
High Selectivity and Sensitivity of Oligomeric p-Phenylene Ethynylenes for Detecting Fibrillar and Prefibrillar Amyloid Protein Aggregates
AM Fanni, FA Monge, CY Lin, A Thapa, K Bhaskar, DG Whitten, EY Chi
ACS Chemical Neuroscience 10 (3), 1813-1825, 2019
Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study
H Ma, A Thapa, LM Morris, S Michalakis, M Biel, MB Frank, M Bebak, ...
Human molecular genetics 22 (19), 3906-3919, 2013
Status paper on road safety in Nepal
AJ Thapa
DDG, Department of Roads. Kathmandu, Nepal 22, 2013
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