Myles Brown

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Xiaole Shirley LiuCEO, GV20 TherapeuticsVerified email at ds.dfci.harvard.edu
Cliff MeyerDana-Farber Cancer Institute and Harvard T.H. Chan School of Public HealthVerified email at jimmy.harvard.edu
Jason CarrollUniversity of CambridgeVerified email at cruk.cam.ac.uk
Tengfei XiaoCTO, GV20 OncotherapyVerified email at bioxbh.com
Housheng Hansen HePrincess Margaret Cancer Centre, University Health Network; Department of Medical BiophysicsVerified email at uhnresearch.ca
Wei LiGrace B. Bell Endowed Chair and Professor of Bioinformatics, University of California IrvineVerified email at uci.edu
Tao LiuAssociate Professor, Roswell Park Comprehensive Cancer CenterVerified email at roswellpark.org
Mathieu Lupien, Ph.D.Senior Scientist/Professor, Princess Margaret Cancer CentreVerified email at uhnresearch.ca
Peng JiangStadtman Tenure-Track Investigator, National Cancer Institute, NIHVerified email at nih.gov
Qianben Wang, Ph.D.Banks Anderson, Sr. Distinguished Professor of Pathology, Duke University School of MedicineVerified email at duke.edu
Yong Zhang 张勇Professor of Bioinformatics, Tongji UniversityVerified email at tongji.edu.cn
Shengqing (Stan) GuThe University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Wei LiChildren's National Hospital, George Washington UniversityVerified email at childrensnational.org
Elgene LimUNSW, Garvan Institute, St Vincent's HospitalVerified email at garvan.org.au
Yiwen ChenAssociate Professor at University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Rachel SchiffBaylor College of MedicineVerified email at bcm.edu
Xintao QiuHarvard Medical School / Dana Faber Cancer InstituteVerified email at dfci.harvard.edu
James DiRenzoCognoscenti ScientificVerified email at dartmouth.edu
Gilles BuchwalterDana-Farber Cancer Institute, Harvard Medical SchoolVerified email at dfci.harvard.edu
Kai WucherpfennigVerified email at dfci.harvard.edu

Myles Brown

Emil Frei III Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School

Verified email at dfci.harvard.edu - Homepage

Epigenetics transcription steroid receptors hormone dependent cancer CRISPR screens


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Model-based analysis of ChIP-Seq (MACS) Y Zhang, T Liu, CA Meyer, J Eeckhoute, DS Johnson, BE Bernstein, ... Genome biology 9, 1-9, 2008	16270	2008
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response P Jiang, S Gu, D Pan, J Fu, A Sahu, X Hu, Z Li, N Traugh, X Bu, B Li, J Liu, ... Nature medicine 24 (10), 1550-1558, 2018	3517	2018
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ... Genome biology 15, 1-12, 2014	2067	2014
Cofactor dynamics and sufficiency in estrogen receptor–regulated transcription Y Shang, X Hu, J DiRenzo, MA Lazar, M Brown Cell 103 (6), 843-852, 2000	2023	2000
Genome-wide analysis of estrogen receptor binding sites JS Carroll, CA Meyer, J Song, W Li, TR Geistlinger, J Eeckhoute, ... Nature genetics 38 (11), 1289-1297, 2006	1631	2006
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1 JS Carroll, XS Liu, AS Brodsky, W Li, CA Meyer, AJ Szary, J Eeckhoute, ... Cell 122 (1), 33-43, 2005	1579	2005
Molecular determinants for the tissue specificity of SERMs Y Shang, M Brown Science 295 (5564), 2465-2468, 2002	1433	2002
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription M Lupien, J Eeckhoute, CA Meyer, Q Wang, Y Zhang, W Li, JS Carroll, ... Cell 132 (6), 958-970, 2008	1122	2008
The CAG repeat within the androgen receptor gene and its relationship to prostate cancer E Giovannucci, MJ Stampfer, K Krithivas, M Brown, A Brufsky, J Talcott, ... Proceedings of the National Academy of Sciences 94 (7), 3320-3323, 1997	1086	1997
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer Q Wang, W Li, Y Zhang, X Yuan, K Xu, J Yu, Z Chen, R Beroukhim, ... Cell 138 (2), 245-256, 2009	1077	2009
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ... Science 338 (6113), 1465-1469, 2012	962	2012
X chromosomal abnormalities in basal-like human breast cancer AL Richardson, ZC Wang, A De Nicolo, X Lu, M Brown, A Miron, X Liao, ... Cancer cell 9 (2), 121-132, 2006	959	2006
Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance SY Ku, S Rosario, Y Wang, P Mu, M Seshadri, ZW Goodrich, ... Science 355 (6320), 78-83, 2017	947	2017
Differential activation of peroxisome proliferator-activated receptors by eicosanoids (∗) K Yu, W Bayona, CB Kallen, HP Harding, CP Ravera, G McMahon, ... Journal of Biological Chemistry 270 (41), 23975-23983, 1995	914	1995
Formation of the androgen receptor transcription complex Y Shang, M Myers, M Brown Molecular cell 9 (3), 601-610, 2002	879	2002
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ... Nature 508 (7494), 103-107, 2014	864	2014
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription S Halachmi, E Marden, G Martin, H MacKay, C Abbondanza, M Brown Science 264 (5164), 1455-1458, 1994	827	1994
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth Q Wang, W Li, XS Liu, JS Carroll, OA Jänne, EK Keeton, AM Chinnaiyan, ... Molecular cell 27 (3), 380-392, 2007	771	2007
Cistrome: an integrative platform for transcriptional regulation studies T Liu, JA Ortiz, L Taing, CA Meyer, B Lee, Y Zhang, H Shin, SS Wong, ... Genome biology 12, 1-10, 2011	750	2011
A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, L Ferrari de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018	745	2018

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